January 26, 2016
…to human airway cells, suppress immune defenses and alter inflammation, while at the same time boosting bacterial virulence. The mouse study is published January 25 by the Journal of Molecular Medicine.
June 8, 2015
…body can help protect against obesity-related diseases by reducing inflammation in the fat tissues. The study, published June 4 in the journal Cell Metabolism, focused on liver and kidney diseases, but the researchers believe it could lead to a new therapeutic approach for a variety of obesity-fueled conditions.
November 25, 2014
The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils.
May 21, 2021
UC San Diego School of Medicine researchers identify how the body regulates and prevents constant skin inflammation.
February 8, 2024
Each cell features mtDNA, instructions that mitochondria use to create energy. When mtDNA remains where it belongs, cells remain healthy. But when it goes where it doesn’t belong, mtDNA can initiate an immune response and inflammation. Scientists have discovered the pathways behind this process.
December 29, 2014
While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found…
November 3, 2016
By removing the protein galectin-3 (Gal3), a team of investigators led by University of California School of Medicine researchers were able to reverse diabetic insulin resistance and glucose intolerance in mouse models of obesity and diabetes.
January 26, 2015
To better understand PLA2 enzymes and help drive therapeutic drug development, researchers at University of California, San Diego School of Medicine developed 3D computer models that show exactly how two PLA2 enzymes extract their substrates from cellular membranes. The new tool is described in a paper published online the week…
January 7, 2021
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns.
February 7, 2018
Treating obese mice with catestatin (CST), a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers.
