August 18, 2014
…cyclooxygenase, thus preventing production of the prostaglandins that cause inflammation and pain, it also prompts the enzyme to generate another compound that hastens the end of inflammation, returning the affected cells to homeostatic health.
October 23, 2017
…gene’s function to chronic inflammation and cancer. Through large-scale genomic analyses, they discovered that “mutant p53” amplifies the impact of inflammation, leading to increases in cancer. Thus, rather than fighting tumor growth, mutant forms of p53 appear to be tapping into the body’s immune response system to fuel pro-inflammatory responses…
August 24, 2011
Inflammatory bowel disease (IBD), which affects more than 1 million patients in North America, results from an uncontrolled immune response triggered by environmental factors, such as bacteria, in people genetically predisposed to the disorder. Ulcerative colitis, or inflammation of the lining of the colon, is one such condition.
July 12, 2023
UC San Diego scientists contest longstanding hypothesis about mysterious illness affecting Gulf War veterans, providing first direct evidence that symptoms are driven by impaired mitochondria.
September 18, 2012
Adah Almutairi, associate professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences, the department of nanoengineering, and the materials science and engineering program at the UC San Diego, and colleagues have developed the first degradable polymer that is extremely sensitive to low but biologically relevant concentrations of hydrogen peroxide.
April 1, 2024
Researchers at UC San Diego have received new grants that will help develop full-body imaging techniques to detect inflammation, which is currently very difficult to visualize in the clinic.
August 9, 2021
UC San Diego Health physicians describe first known case of young, healthy adult experiencing central nervous system inflammation due to COVID-19, but without cognitive impairment.
May 1, 2012
…distinct articles exploring: the complex interactions of lipids and inflammation in insulin resistance; the roles of omega 3 fatty acids and a particular gene in fighting inflammation;how elevated levels of a particular protein might delay the muscle-destroying effects of amyotrophic lateral sclerosis.
February 25, 2016
Inflammation is a Catch-22: the body needs it to eliminate invasive organisms and foreign irritants, but excessive inflammation can harm healthy cells, contributing to aging and sometimes leading to organ failure and death. Researchers at University of California, San Diego School of Medicine have discovered that a protein known as…
September 18, 2018
…(GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.
