September 18, 2018
September 18, 2018 —
…(GPCRs) and their cellular waste disposal systems to control inflammation. The findings, published September 18 in Cell Reports, suggest some existing cancer drugs that inhibit these cellular activities might be repurposed to treat vascular inflammation, which occurs when artery-blocking plaques form in atherosclerosis.
June 16, 2021
June 16, 2021 —
Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they’re needed.
June 6, 2018
June 6, 2018 —
…that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged…
May 15, 2012
May 15, 2012 —
…may be possible to manipulate these processes to short-circuit inflammation before it begins, or at least help to resolve inflammation before it becomes detrimental.
March 4, 2021
March 4, 2021 —
A study by researchers from the Salk Institute and UC San Diego opens a potential new avenue for clinical intervention in a psychiatric disease.
February 8, 2018
February 8, 2018 —
Ever wonder why obese bodies burn less calories or why dieting often leads to a plateau in weight loss? In both cases the body is trying to defend its weight by regulating energy expenditure. In a paper publishing in Cell on February 8, University of California San Diego School of…
May 12, 2021
May 12, 2021 —
Researchers at UC San Diego School of Medicine have begun a pilot clinical trial to test the efficacy of using ultrasound to stimulate the spleen and reduce COVID-19-related inflammation, decreasing the length of hospital stays.
November 3, 2015
November 3, 2015 —
…biomarkers of cancer risk, such as insulin resistance and inflammation.
February 23, 2015
February 23, 2015 —
…have discovered that the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. What’s more, the team found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves insulin sensitivity in obese mice. The study is published Feb.…
April 10, 2012
April 10, 2012 —
…a chronic digestive disease that can lead to severe inflammation, stricture, Barrett’s esophagus and esophageal cancer.