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Your search for “Animal Models” returned 337 results

A New Strategy to Transform Liver Cancer Immunotherapy

December 7, 2021

UC San Diego researchers identify new strategy to improve efficacy of immunotherapy on resistant liver cancers.

Brain Cells Under Attack Don ‘Body Armor’ Response, Offering New Views of Stroke Damage

December 13, 2022

UC San Diego neurobiologists have discovered that cells within neurons, the brain’s transmission connectors, protect themselves with a type of body armor when faced with threatening conditions such as during a stroke. The pro-survival mechanism helps reduce brain tissue damage.

Weak Brain Circadian Rhythms Cause Depression-Like Behavior in Mice

May 2, 2016

When the master pacemaker that normally synchronizes circadian rhythms in the brain is disrupted, that disruption causes helplessness, behavioral despair, and anxiety-like behavior in mice, say scientists at the University of California San Diego.

Super Productive 3D Bioprinter Could Help Speed Up Drug Development

June 8, 2021

A new 3D bioprinter developed by UC San Diego nanoengineers operates at record speed—it can print a 96-well array of living human tissue samples within 30 minutes. The technology could help accelerate high-throughput preclinical drug screening and make it less costly.

Computer Science Researchers Are Getting it Wrong When it Comes to Autism Inclusivity

August 6, 2024

Computer science Ph.D. student Naba Rizvi investigates the stereotypes about neurodiversity perpetuated by computer science research in a new study.

Flipping a Metabolic Switch to Slow Tumor Growth

August 12, 2020

The enzyme serine palmitoyl-transferase can be used as a metabolically responsive “switch” that decreases tumor growth, according to a new study by a team of San Diego scientists, who published their findings Aug. 12 in the journal Nature.

Following Cellular Lineage

April 16, 2024

A group of researchers based at UC San Diego and Rady Children’s Institute have advanced the understanding of how the cerebral cortex develops by tracing the lineage of certain brain cells.

Stem Cell Therapy Rescues Symptoms of Alzheimer’s Disease

August 9, 2023

Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.

San Diego Supercomputer Center Plays a Role in NSF’s New ICICLE Institute

July 29, 2021

The AI Institute for Intelligent Cyberinfrastructure with Computational Learning in the Environment, or ICICLE, will focus on next-generation intelligent cyberinfrastructure that makes using AI as easy as plugging an appliance into an electrical outlet.

Novel Autism Mouse Model Based on an Epigenetic Gene Developed

January 30, 2019

In a study published January 17, 2019 in Translational Psychiatry, researchers at University of California San Diego School of Medicine describe how, in a novel mouse model, epigenetic regulation negatively impacts a downstream gene specifically involved in neurodevelopment and associated behaviors.

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