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Your search for “Animal Models” returned 337 results

Human Brain Organoids Implanted into Mouse Cortex Respond to Visual Stimuli for First Time

December 28, 2022

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals’ cortex and responded to external sensory stimuli.

Jacobs School Shines at Fluid Dynamics Conference

November 20, 2012

…a better way to model climate in urban areas; and optimized blood flow patterns for heart patients with pacemakers. Fluid dynamics researchers from the University of California, San Diego, are discussing their research on these topics—and many others—at the 65th Annual Meeting of the American Physical Society’s Division of Fluid…

Ambitious Project to Understand Cellular Evolution Underway

October 6, 2020

Project focuses on lipids (fat molecules) as the starting point to understand the evolution of eukaryotic cells, carrying implications for human health and disease

Before There Will Be Blood

November 6, 2014

Researchers at the University of California, San Diego School of Medicine describe the surprising and crucial involvement of a pro-inflammatory signaling protein in the creation of hematopoietic stem cells (HSCs) during embryonic development, a finding that could help scientists to finally reproduce HSCs for therapeutic use.

Stem Cells Regenerate Human Lens After Cataract Surgery, Restoring Vision

March 9, 2016

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses.

Small Molecule Drug Reverses ADAR1-induced Cancer Stem Cell Cloning Capacity

February 16, 2023

UC San Diego researchers report that a late-stage, pre-clinical small molecule inhibitor reverses malignant hyper-editing by a protein that promotes silencing of the immune response, metastasis and therapeutic resistance in 20 different cancer types.

Herpes Infected Humans Before They Were Human

June 10, 2014

Researchers at the University of California, San Diego School of Medicine have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors…

UC San Diego Launches New Center for Anti-Parasitic Drug Discovery and Development

June 13, 2018

Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the…

Brain Organoids Reveal in Detail the Harms of Prenatal Alcohol Exposure

November 18, 2022

UC San Diego researchers used human brain organoids to study the effects of prenatal alcohol exposure on neural development, revealing significant harms in molecular detail.

UC San Diego Receives $12.4M NIH Grant to Map the Human Nervous System

February 23, 2022

The National Institutes of Health have awarded UC San Diego a grant totaling $12.4 million. This will support a new research center dedicated to studying the human brain and central nervous system 〈CNS〉, specifically the ways they’re affected by HIV and opioids.

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