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Your search for “Animal Models” returned 337 results

New Grant Will Fund Collaborative Effort to Build Reproducible Assays To Model Autism

September 22, 2015

The National Institutes of Health has awarded a $13 million grant over five years to develop and disseminate new stem cell-based technologies and assays for studying autism spectrum disorder (ASD) and other mental health diseases to a consortium of researchers at the University of California, San Diego and the Salk…

Unraveling a Key Junction Underlying Muscle Contraction

July 31, 2024

Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal kingdom and setting the stage for possible future treatments for muscular disorders.

Cooked Crustaceans, Cannabis and a Budder Way

June 29, 2021

Researchers expose live lobsters to vaporized cannabis and confirm the crustaceans absorb THC. Whether the psychoactive compound affects behavior remains open question.

Why the Seahorse’s Tail is Square and How It Could be an Inspiration for Robots and Medical Devices

July 2, 2015

Why is the seahorse’s tail square? An international team of researchers has found the answer and it could lead to building better robots and medical devices. In a nutshell, a tail made of square, overlapping segments makes for better armor than a cylindrical tail. It’s also better at gripping and…

Experimental Drug Blocks Toxic Ion Flow Linked to Alzheimer’s Disease

December 5, 2017

…memory in a mouse model of Alzheimer’s disease. The molecule, called anle138b, works by stopping toxic ion flow in the brain that is known to trigger nerve cell death. Scientists envision that this drug could be used to treat Alzheimer’s and other neurodegenerative diseases such as Parkinson’s and ALS.

Developmental Protein Plays Role in Spread of Cancer

June 14, 2013

A protein used by embryo cells during early development, and recently found in many different types of cancer, apparently serves as a switch regulating the spread of cancer, known as metastasis, report researchers at the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center…

Human Lung and Brain Organoids Respond Differently to SARS-CoV-2 Infection in Lab Tests

February 24, 2021

UC San Diego School of Medicine researchers are using stem cell-derived organoids to study how SARS-CoV-2 interacts with various organ systems. Their findings may help explain the wide variety in COVID-19 symptoms and aid the search for therapies.

In Mice, Alcohol Dependence Results in Brain-Wide Remodeling of Functional Architecture

January 14, 2020

Using novel imaging technologies, researchers produce first whole-brain atlas at single-cell resolution, revealing how alcohol addiction and abstinence remodel neural physiology and function in mice.

Artificial Neural Networks Learn Better When They Spend Time Not Learning at All

November 18, 2022

UC San Diego researchers discuss how mimicking sleep patterns of the human brain in artificial neural networks may help mitigate the threat of catastrophic forgetting in the latter, boosting their utility across a spectrum of research interests.

In Multiple Myeloma, High Levels of Enzyme ADAR1 are Associated with Reduced Survival

December 5, 2017

Using a database of multiple myeloma patient samples and information, researchers at University of California San Diego School of Medicine found that high ADAR1 levels correlate with reduced survival rates. They also determined that blocking the enzyme reduces multiple myeloma regeneration in experimental models derived from patient cancer cells.

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