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Your search for “Animal Models” returned 337 results

SDSC Assists Researchers in Novel Wildlife Tracking Project

July 2, 2014

A team including researchers from the U.S. Geological Survey (USGS) and the San Diego Zoo’s Institute for Conservation Research has developed a novel methodology that for the first time combines 3D and advanced range estimator technologies to provide highly detailed data on the range and movements of terrestrial, aquatic, and…

New Drug Successfully Halts Fibrosis in Animal Model of Liver Disease

August 7, 2012

A study published in the online journal Hepatology reports a potential new NADPH oxidase (NOX) inhibitor therapy for liver fibrosis, a scarring process associated with chronic liver disease that can lead to loss of liver function.

Human Mini-Lungs Grown in Lab Dishes are Closest Yet to Real Thing

August 31, 2021

UC San Diego researchers developed first-of-their-kind lung organoids that include all cell types that make up the organ, allowing for “Phase 0” testing of new treatments for respiratory infections such as COVID-19.

Researchers Identify Brain Circuits Tied to the Behavior of Schooling Fish

July 17, 2024

UC San Diego researchers have uncovered the roots of group behavior in the brains of schooling fish. Glassfish, they found, depend on their sense of vision to coordinate social swimming behavior in schools and increase their ability to follow coordinated group movements as they mature.

Drug Found for Parasite that is Major Cause of Death Worldwide

May 21, 2012

Research by a collaborative group of scientists from UC San Diego School of Medicine, UC San Francisco and Wake Forest School of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death…

Early Life Exposure to Nicotine Alters Neurons, Predisposes Brain to Addiction Later in Life

May 21, 2019

Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a published study.

Novel Drug Prevents Amyloid Plaques, a Hallmark of Alzheimer’s Disease

March 2, 2021

Researchers at UC San Diego School of Medicine and elsewhere have identified a new drug that could prevent AD by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques.

UC San Diego Researchers First to Use CRISPR/Cas9 to Control Genetic Inheritance in Mice

January 23, 2019

Using active genetics technology, biologists have developed the world’s first CRISPR/Cas9-based approach to control genetic inheritance in a mammal. The achievement in mice lays the groundwork for further advances based on this technology, including biomedical research on human disease.

UC San Diego and Samsara Sciences Team Up to Advance Liver Tissue Models

January 14, 2016

Researchers at University of California, San Diego School of Medicine and Samsara Sciences, Inc., a wholly-owned subsidiary of Organovo Holdings, Inc., have entered into an agreement focused on the development of techniques and methods for the isolation and characterization of liver cells that will help drive new research on liver…

Worms Reveal Secrets of Wound Healing Response

November 17, 2011

The lowly and simple roundworm may be the ideal laboratory model to learn more about the complex processes involved in repairing wounds and could eventually allow scientists to improve the body’s response to healing skin wounds, a serious problem in diabetics and the elderly.

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