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Your search for “Animal Models” returned 337 results

One in the Hand Worth Two in the Bush? Tendency to Undervalue Future Rewards Linked to ADHD, Obesity

December 11, 2017

Researchers at University of California San Diego School of Medicine have found a genetic signature for delay discounting — the tendency to undervalue future rewards — that overlaps with attention-deficit/hyperactivity disorder (ADHD), smoking and weight.

Small Loop in Human Prion Protein Prevents Chronic Wasting Disease

February 23, 2015

…humans. Using a mouse model that expresses an altered form of the normal human prion protein, researchers at University of California, San Diego School of Medicine have determined why the human proteins aren’t corrupted when exposed to the elk prions. Their study identifies a small loop in the human prion…

Studies Reveal How Cells Distinguish Between Disease-Causing and Innocuous Invaders

April 12, 2012

A study conducted on roundworms by biologists at UC San Diego has uncovered some important clues to answering the question of how humans and other animals are able to discriminate between disease-causing microbes and innocuous ones to rapidly respond to infections.

Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models

May 11, 2016

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first “direct experimental proof” that the Brazilian strain of Zika virus can actually cause severe birth defects. The findings are published in the May 11 online issue of Nature.

Supercomputer Simulations Help Combat Tuberculosis (TB) Granulomas

March 20, 2019

Researchers from the University of Michigan relied on supercomputers at UC San Diego and elsewhere to help them develop detailed models to better understand how TB spreads throughout the lungs.

A Fish Story with a Human Tell

February 17, 2022

Researchers at University of California San Diego School of Medicine and in Japan have used an ancient fish to reel in new insights about human biology and, in particular, how and why a widely used medication works to abort pregnancies (in people, not fish).

Plant Virus Plus Immune Cell-Activating Antibody Clear Colon Cancer in Mice, Prevent Recurrence

June 21, 2022

A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system’s “natural killer” cells, shows a study by UC San Diego researchers. In mouse models of colon cancer, the therapy eliminated all tumors and prevented their recurrence.

Researchers ID ‘Conjunction Junction’ for Brain’s Navigation Function

July 9, 2015

Ever wake at night needing a drink of water and then find your way to the kitchen in the dark without stubbing your toe? Researchers at the University of California, San Diego say they have identified a region of the brain that enables you to do that – and generally…

Proof of Pimple: Mouse Model Validates How “Good” and “Bad” Bacteria Affect Acne

March 7, 2019

Researchers at UC San Diego School of Medicine generated a new mouse model that mimics human acne for the first time, and used it to validate the concept of “good” and “bad” acne bacteria and introduce new possibilities for targeted treatments and vaccines.

UC San Diego’s Tsien Honored with First-Ever “Golden Goose Award”

September 13, 2012

Roger Tsien, PhD, professor of pharmacology, chemistry and biochemistry at the University of California, San Diego School of Medicine who shared the 2008 Nobel Prize in chemistry for his role in helping develop and expand the use of green fluorescent proteins (GFP) was honored today with one of the first-ever…

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