December 16, 2024
After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, shutting down the protective vaccine response. But blocking the protein restores vaccine efficacy in an animal model.
October 3, 2011
Kumar Sharma, MD, FAHA, professor of medicine at the University of California, San Diego School of Medicine and director of the Center for Renal Translational Medicine, has received a $5.9 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of…
March 13, 2019
New preclinical data from University of California San Diego School of Medicine and Moores Cancer Center offers proof-of-principle for a combination immunotherapy that suppresses tumor growth in the liver. Current therapies for liver cancer are largely ineffective, resulting in poor outcomes.
July 9, 2018
Many insects and animals have special proteins that act like car antifreeze to prevent ice from forming and spreading in their bodies amidst harsh winter temperatures. Scientists know about these antifreeze proteins (AFPs), but not so much about the mechanisms that make them work. Chemistry researchers at the University of…
April 26, 2018
…able to bring extinct animals back to life, big questions emerge. What led to extinction in the first place? What would be the impacts on other species or the environment? Just because we can do it, does that mean we should? From left, sociologist John Evans, Division of Arts and…
January 29, 2015
Researchers at San Diego State University and the University of California, San Diego, shed new light on how whales are able to hear, and more specifically on the role of the skulls of at least some baleen whales—fin whales to be precise.
September 10, 2024
…may impact the nervous systems and behavior of marine animals.
December 4, 2014
The bacterium Salmonella Typhi causes typhoid fever in humans, but leaves other mammals unaffected. Researchers at University of California, San Diego and Yale University Schools of Medicine now offer one explanation — CMAH, an enzyme that humans lack. Without this enzyme, a toxin deployed by the bacteria is much better…
May 14, 2014
…is produced naturally in small quantities in humans and animals, and in recent years medical researchers have evaluated the gas as a treatment for diabetes, heart attacks, sepsis, and other illnesses.
July 7, 2022
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
