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Your search for “Cancer Mutations” returned 220 results

Genetic Variation in Individual Brain Cell Types May Predict Disease Risk

November 14, 2019

Researchers identified non-coding regions of the human genome that control the development and function of four brain cell types and mapped genetic risk variants for psychiatric diseases. They found that risk variants for Alzheimer’s disease were enriched in microglia-specific regulatory elements.

Leading-edge Technology Unmasks Protein Linked to Parkinson’s Disease

August 19, 2020

An elusive protein that many consider the key of fully understanding the causes of genetic Parkinson’s disease has come much more clearly into focus. Impacting millions around the world, Parkinson’s is a neurological disorder that progressively attacks motor functions.

Two Billion Reasons to Celebrate

August 19, 2019

…From student scholarships to cancer vaccines, the Campaign for UC San Diego is changing lives It was an ambitious and lofty goal. But for our university, overachieving is the norm. When the Campaign for UC San Diego was launched in 2012, the focus of the 10-year, $2 billion comprehensive fundraising…

The Mouse That ROR’ed

January 2, 2014

Researchers at the University of California, San Diego School of Medicine report that an oncogene dubbed ROR1, found on chronic lymphocytic leukemia (CLL) B cells but not normal adult tissues, acts as an accelerant when combined with another oncogene, resulting in a faster-developing, more aggressive form of CLL in mice.

Scientists Uncover Strong Support for Once-Marginalized Theory on Parkinson’s Disease

April 25, 2012

University of California, San Diego scientists have used powerful computational tools and laboratory tests to discover new support for a once-marginalized theory about the underlying cause of Parkinson’s disease.

Programming probiotics for early detection of liver cancer

June 1, 2015

…method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present. The results of the new study, published in the May 27 issue of Science Translational Medicine, indicate that genetically-programmed probiotics may be…

Harnessing Human Evolution to Advance Precision Medicine

February 9, 2024

Scientists hope to advance precision medicine through the discovery of a gene variant that leads to the same phenotype in separate high-dwelling populations while taking a different evolutionary path.

Five UC San Diego Jacobs School of Engineering Graduate Students Named 2013 Siebel Scholars

September 19, 2012

Five University of California, San Diego graduate students pursuing research at the intersection of bioengineering, medicine and biology are among the 85 recipients of 2013 Siebel Scholars awards, announced by the Siebel Scholars Foundation on September 10, 2012.

Smartly Done

May 18, 2023

Across disciplines and specialties, from cells to systems, artificial intelligence is on its way to altering how we understand and treat disease.

Corrected Protein Structure Reveals Drug Targets for Cancer, Neurodegenerative Diseases

August 13, 2015

Protein Kinase C is a family of enzymes that controls the activity of other proteins in a cell by attaching chemical tags. That simple act helps determine cell survival or death. When it goes awry, a number of diseases may result. In a study, researchers at University of California, San…

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