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Your search for “Cancer Mutations” returned 226 results

SDSC/UC San Diego Researchers Hone in on Alzheimer’s Disease

February 18, 2014

Researchers studying peptides using the Gordon supercomputer at the San Diego Supercomputer Center (SDSC) at the University of California, San Diego (UCSD) have found new ways to elucidate the creation of the toxic oligomers associated with Alzheimer’s disease.

UC San Diego Joins National Trial to Explore New Vaccines for COVID-19 Variants

April 6, 2022

UC San Diego has joined a Phase II clinical trial to evaluate various additional COVID-19 booster shots. The trial seeks to understand if different vaccine regimens can broaden immune responses in adults who already have received a primary vaccination series and a first booster shot.

When the Language of Cells is Interrupted

November 12, 2020

…of control, leading to cancer. A slowdown of the same kinase may contribute to untimely cell death, as might occur in neurodegenerative diseases, such as Alzheimer’s. Drug discovery If we know what has gone wrong, we are in a better position to fix it, Newton said. “Let’s say you are…

Underappreciated Protein Plays Critical Role In RNA Regulation and Male Fertility

March 31, 2016

A protein once thought to be of little consequence has been found to be a central player in processes ranging from male fertility to early embryonic development, according to a study published in the March 31 online issue of Cell by researchers at the University of California, San Diego School…

Three UC San Diego Professors Named Recipients of 2018 Breakthrough Prize

December 3, 2017

Two full-time University of California San Diego faculty members — Don Cleveland, who studies fundamental cellular mechanisms in the search for new treatments for diseases like amyotrophic lateral sclerosis (ALS), and James McKernan, a mathematician who investigates algebraic geometry and multivariate polynomials — are recipients of the 2018 Breakthrough Prize,…

Mini-brain Model of Idiopathic Autism Reveals Underlying Pathology of Neuronal Overgrowth

July 13, 2016

The majority of cases of autism spectrum disorder (ASD) are unknown. In a paper published in the journal Molecular Psychiatry, researchers at the University of California San Diego School of Medicine, with colleagues across the nation and world, have created a “mini-brain” model, derived from persons with a particular form…

Shooting for the Stars

January 23, 2024

UC San Diego scientists are sending cells into space and health science into the future.

Synthetic Biology Used to Limit Bacterial Growth and Coordinate Drug Release

July 20, 2016

…The team engineered a clinically relevant bacterium to produce cancer drugs and then self-destruct and release the drugs at the site of tumors. The approach enables continual production and release of drugs at disease sites in mice while simultaneously limiting the size, over time, of the populations of bacteria engineered…

When Ancient Fossil DNA Isn’t Available, Ancient Glycans May Help Trace Human Evolution

September 11, 2017

Researchers at University of California San Diego School of Medicine and collaborators discovered a new kind of glycan (sugar chain) that survives even in a 4 million-year-old animal fossil from Kenya, under conditions where ancient DNA does not. While ancient hominin fossils are not yet available for glycan analysis, this…

New ‘Atlas’ Provides Unprecedented Insights on How Genes Function in Early Embryo Development

May 23, 2024

UC San Diego biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new “gene atlas” with 4D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

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