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Your search for “gene therapy” returned 759 results

Therapeutic Potential of Bizarre ‘Jumbo’ Viruses Tapped for $10M HHMI Emerging Pathogens Project

January 26, 2023

UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.

Study: Breast Cancer Drug Shows Potential for Rare Appendix Cancer

October 16, 2024

UC San Diego School of Medicine researchers discover a groundbreaking oral breast cancer drug that is also effective in treating a rare form of appendix cancer.

With a $50 Million Gift, USC and UC San Diego Join Forces in Alzheimer’s Research

January 24, 2022

A joint gift to the University of Southern California (USC) and the University of California San Diego totaling $50 million from the Epstein Family Foundation will drive Alzheimer’s research and accelerate the search for treatments and a cure.

Nanopillars Create Tiny Openings in the Nucleus Without Damaging Cells

October 2, 2024

…“gateway into the nucleus” could open new possibilities in gene therapy, where genetic material needs to be delivered directly into the nucleus, as well as drug delivery and other forms of precision medicine.

Researchers Block Pathway to Cancer Cell Replication

July 3, 2012

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…

Access Denied: Leukemia Thwarted by Cutting Off Link to Environmental Support

July 29, 2015

A new study by researchers at University of California, San Diego School of Medicine reveals a protein’s critical – and previously unknown – role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer. The finding offers a novel target for better treating…

Gene Mutation Found for Aggressive Form of Pancreatic Cancer

May 25, 2014

Researchers at the University of California, San Diego School of Medicine have identified a mutated gene common to adenosquamous carcinoma (ASC) tumors – the first known unique molecular signature for this rare, but particularly virulent, form of pancreatic cancer.

Groundbreaking Research Paves the Way for Acne Vaccine

December 20, 2023

In a groundbreaking development in the field of anti-acne therapies, a team of researchers has created an acne vaccine that, when used in a mouse acne model, neutralizes a specific variant of an enzyme produced by an acne-associated bacteria while leaving the healthy bacterial enzyme intact.

Vinculin protein boosts function in the aging heart

June 17, 2015

…over a lifetime despite the fact that most organisms generate few new heart cells. Identifying key gene expression changes that promote heart function as organisms age could lead to new therapy targets that address age-related heart failure.

Leukemia in Remission for First Patient to Undergo CAR T-Cell Immunotherapy in San Diego

August 4, 2016

…a new type of immunotherapy, known as CAR T-cell therapy, as part of a Phase I/II clinical trial at Moores Cancer Center at UC San Diego Health.

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