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Your search for “gene therapy” returned 49 results

Gene Therapy Finds New Life in an Old Home

November 10, 2022

Gene Therapy Finds New Life in an Old Home

How Gene Therapy May Hold Key to Treating Life-Threatening Cardiac Disease

March 18, 2020

…treat Danon disease using gene therapy. “Heart transplant is not always available for patients, and does not treat the other organs affected in Danon disease,” said Eric Adler, MD, principal investigator of the study. Adler is a cardiologist at UC San Diego Health and director of cardiac transplant and mechanical…

Friedmann Recognized for Pioneering Gene Therapy Research

January 29, 2015

Friedman Recognized for Pioneering Gene Therapy Research School of Medicine professor receives prestigious Japan Prize Theodore Friedmann Theodore Friedmann, MD, professor in the Department of Pediatrics at University of California, San Diego School of Medicine was named today one of three recipients of the 2015 Japan Prize, a prestigious international…

Gene Therapy in Alzheimer’s Disease Mouse Model Preserves Learning and Memory

May 4, 2021

…colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease. The findings are published online in advance of the June 11, 2021 issue of Molecular Therapy–Methods…

Southern California’s First Real-Time MRI-Guided Gene Therapy for Brain Cancer

August 6, 2013

…guidance for delivery of gene therapy as a potential treatment for brain tumors. Using MRI navigational technology, neurosurgeons can inject Toca 511 (vocimagene amiretrorepvec), a novel investigational gene therapy, directly into a brain malignancy. This new approach offers a precise way to deliver a therapeutic virus designed to make the…

Degenerating Neurons Respond to Gene Therapy Treatment for Alzheimer’s Disease

August 27, 2015

…responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology. The affected neurons displayed heightened growth, axonal sprouting and activation of functional markers, said lead…

Gene Therapy Approach Shows Promise in Treating ALS

August 2, 2022

…Medicine report that a gene therapy approach, developed at UC San Diego, measurably delayed disease onset in humanized mouse and rat models of familial ALS, an inherited form of the disease that runs in families. (Most ALS cases are sporadic, of unknown cause, though environmental and genetic factors may play…

First-in-Human Clinical Trial to Assess Gene Therapy for Alzheimer’s Disease

February 18, 2021

…and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer’s disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia. The protein, called brain-derived neurotrophic factor or BDNF, is part of a family of growth factors found in…

Friedmann Named 2015 Japan Prize Winner

January 28, 2015

…to the development of gene therapy, a new field of medicine which in significant ways originated at UC San Diego. The sponsoring Japan Prize Foundation describes Friedmann as “the father of gene therapy.” Sharing the 2015 Japan Prize “in the field of medical science and medicinal science” with Friedman is…

Scientists Race to Outpace Lethal Bacterial Infections

May 30, 2018

…example of an effective gene therapy for deadly bacterial infections. In a paper recently published in the journal Nature Communications, UC San Diego Department of Chemistry and Biochemistry’s Michael Sailor, along with colleagues from the Sanford Burnham Prebys Medical Discovery Institute (SBP), the University of Minnesota and the Korea Advanced…

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