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Your search for “gene therapy” returned 759 results

Immune Cells Infiltrating Tumors May Play Bigger Cancer Role Than Previously Thought

June 22, 2020

UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells’ response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making IRE1α an attractive target for drug development.

A New Gene-Editing System Tackles Complex Diseases

May 21, 2024

Current methods to model or correct mutations in live cells are inefficient, especially when multiplexing — installing multiple point mutations simultaneously across the genome. Researchers from the UC San Diego have developed new, efficient genome editing tools called multiplexed orthogonal base editors (MOBEs) to install multiple point mutations at once.…

Roche Funds Drug Discovery Projects at UC San Diego

January 9, 2012

The new UC San Diego-Roche Extending Innovation Network (EIN) program has been launched with selection of its first three research projects at the University of California, San Diego School of Medicine.

Philanthropists Ignite the Fight Against Cancer at SPARK Gala April 16

April 12, 2016

To rally the San Diego region in the fight against cancer, the University of California San Diego’s Moores Cancer Center will host its annual SPARK Gala on Saturday, April 16 at the Fairmont Grand Del Mar. The evening will include a three-course dinner with wine pairings, a live luxury auction…

DrugCell: New Experimental AI Platform Matches Tumor to Best Drug Combo

October 22, 2020

UC San Diego researchers use experimental artificial intelligence system called DrugCell to predict the best approach to treating cancer. Only 4 percent of all cancer therapeutic drugs under development earn final approval by the U.S. Food and Drug Administration (FDA).

Clinical Study Suggests the Origin of Glioblastoma Subtypes

May 4, 2016

Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to…

AI Harnesses Tumor Genetics to Predict Treatment Response

January 18, 2024

Cancer resists treatment in a multitude of ways, but a new algorithm developed by scientists at UC San Diego can decode them all simultaneously.

How to Speed Up Muscle Repair

March 17, 2021

By studying how different pluripotent stem cell lines build muscle, researchers have for the first time discovered how epigenetic mechanisms can be triggered to accelerate muscle cell growth, providing new insights for developing therapies for muscle disease, injury and atrophy.

Changing Lives: Carol Vassiliadis Names Hospital with $8.5 Million to Jacobs Medical Center

October 16, 2014

…need them. Together, with generous donors like Carol, we are creating a healthier world, one patient at a time.” “We express our sincere gratitude to Carol for this transformative gift to UC San Diego,” said David Brenner, MD, Vice Chancellor for Health Sciences and Dean of the UC San Diego…

High School Students Learn the Basics of Base Editing to Cure “GFP-itis”

May 4, 2023

Chemistry professor Alexis Komor’s lab designed the Genome Editing Technologies Program as a way to educate high school students on gene-editing technologies and expose them to a possible career in STEM.

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