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Your search for “Therapy Target” returned 457 results

UC San Diego Researchers Isolate Switch that Kills Inactive HIV

September 24, 2019

University of California San Diego School of Medicine researchers have identified a switch controlling HIV reproduction in immune cells which can eliminate dormant HIV reservoirs.

Researchers ID Natural Products with Potential Efficacy Against Coronavirus, Other Lethal Viruses

January 5, 2021

Researchers describe the biology of three families of RNA viruses including Coronavirus, Ebola, and Zika and the natural products that have been shown to have capabilities to inhibit them. The review provides a guide that could accelerate drug discovery in response to future epidemics.

Reversing Cancer’s Gluttony

March 18, 2021

Researchers at UC San Diego School of Medicine and Moores Cancer Center describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

Scientists Race to Outpace Lethal Bacterial Infections

May 30, 2018

…by demonstrating the first example of an effective gene therapy for deadly bacterial infections.

Target Identified For Rare Inherited Neurological Disease In Men

August 10, 2014

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility.

$150 Million Gift Takes Stem Cell Research to New Heights

September 6, 2022

Noted businessman and philanthropist T. Denny Sanford has committed $150 million in new funding to expand and, in some ways, quite literally launch stem cell research and regenerative medicine at University of California San Diego into new spaces and endeavors.

Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes

August 8, 2019

The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor’s root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.

Chemical Disguise Transforms RNAi Drug Delivery

November 17, 2014

Researchers at University of California, San Diego School of Medicine have developed a way to chemically disguise RNAi drugs so that they are able to enter cells. Once inside, cellular machinery converts these disguised drug precursors — called siRNNs — into active RNAi drugs.

Nutrients Turn on Key Tumor Signaling Molecule, Fueling Resistance to Cancer Therapy

July 13, 2015

…other nutrients to resist targeted therapies directed at specific cellular molecules, according to researchers at University of California, San Diego School of Medicine and Ludwig Cancer Research. In the study, published this week in Proceedings of the National Academy of Sciences, the team used human tissue and mouse models to…

New Clinic Matches Patients with Cancer to Latest Precision Immunotherapy Treatments

October 17, 2019

New Precision Immunotherapy Therapy clinic at Moores Cancer Center at UC San Diego Health matches patients using genetic profiling to personalized cancer treatment plans.

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