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Your search for “Therapy Target” returned 440 results

Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

February 18, 2021

Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.

New Resource Makes Gene Editing Technology Even More User-Friendly

July 17, 2015

…CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential to facilitate new discoveries in gene therapies and basic genetics research. The research was published in the July 13 issue of Nature Methods.

Researchers ID Cancer Gene-Drug Combinations Ripe for Precision Medicine

July 21, 2016

…that can be specifically targeted with personalized therapies, researchers at University of California San Diego School of Medicine and Moores Cancer Center looked for combinations of mutated genes and drugs that together kill cancer cells. The study, published July 21 in Molecular Cell, uncovered 172 new combinations that could form…

CAR-T Immunotherapies May Have a New Player

June 29, 2018

…of patient’s T-cells to target and kill cancer cells. In a new study, researchers at University of California San Diego School of Medicine and University of Minnesota report that similarly modified natural killer (NK) cells derived from human induced pluripotent stem cells (iPSCs) also displayed heightened activity against a mouse…

UC San Diego Researcher Receives $6.25 Million Grant

October 14, 2013

The Leukemia & Lymphoma Society has awarded Thomas J. Kipps, MD, PhD, Distinguished Professor of Medicine at the University of California, San Diego School of Medicine, with a 5-year, $6.25 million Specialized Center of Research program grant to support research on chronic lymphocytic leukemia.

New Cancer Therapy Target Stops Tumor Cells From Sharing Resources

October 17, 2023

Researchers at University of California San Diego have discovered a process in which liver cells share molecules in order to multiply under conditions that would ordinarily suppress cell proliferation. They also found evidence that this process occurs in various types of cancer cells.

Simulated Chemistry: New AI Platform Designs Tomorrow’s Cancer Drugs

May 6, 2024

Researchers from University of California San Diego have developed a new AI tool to that generate new drug candidates for cancer, which could help streamline the typically laborious drug discovery process.

CIRM Approves $5.8 Million Grant for CAR-T Therapy that Targets Cancer Stem Cells

July 20, 2017

…be equipped with a special receptor that recognizes and targets cancer stem cells, whose survival abilities often render standard therapies ineffective or short-term.

New Drug Combo Targets Multiple Cancers

November 16, 2011

Researchers at the University of California, San Diego School of Medicine and Kyushu University Medical School say a novel combination of a specific sugar molecule with a pair of cell-killing drugs prompts a wide variety of cancer cell types to kill themselves, a process called apoptosis or programmed cell death.

UC San Diego Cancer Researchers Receive $4 Million CIRM Disease-Team Grant

December 13, 2013

Researcher Thomas J. Kipps, MD, PhD, professor of medicine and deputy director of research operations at UC San Diego Moores Cancer Center, is principal investigator for one of six “Disease Team” awards approved December 12 by the governing board of the California Institute for Regenerative Medicine (CIRM).

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