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Your search for “Therapy Target” returned 457 results

Clinical Study Suggests the Origin of Glioblastoma Subtypes

May 4, 2016

Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to…

$6.4 Million Grant Funds Glaucoma Study in African-Americans

October 11, 2013

A study led by Robert N. Weinreb, chairman and Distinguished Professor of Ophthalmology at the University of California, San Diego School of Medicine, has received a $6.4 million, 5-year grant from the National Eye Institute, part of the National Institutes of Health, to elucidate the genetics of glaucoma in persons…

Cytomegalovirus Infection Relies on Human RNA-Binding Protein

October 24, 2016

…protein called CPEB1. The study provides a potential new target for the development of CMV therapies.

At Initial Cancer Diagnosis, a Deeply Personalized Assessment

October 13, 2021

UC San Diego researchers report that conducting genomic evaluations of advanced malignancies can be effective in guiding first-line-of-treatment, rather than waiting until standard-of-care therapies have failed.

Nanosponges Could Intercept Coronavirus Infection

June 17, 2020

Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce.

UC San Diego Chemist Stirs Hope for a New Flu Treatment

March 19, 2018

Each year people all over the world die from the flu. To protect against influenza epidemics and their potentially mortal results, medical professionals encourage vaccination. While generally effective for healthy individuals, vaccinations are less effective for the elderly, the immunocompromised and other high-risk groups. For the healthy, getting a shot…

10 Cancer Moonshot Blue Ribbon Panel Recommendations Embraced by NCI

September 7, 2016

When 28 distinguished individuals convened earlier this year to help shape the scientific mission at the National Cancer Institute (NCI) of Vice President Joe Biden’s National Cancer Moonshot Initiative, they were given five months to draft guidelines to accelerate cancer research, prevention and care. On Wednesday, the National Cancer Advisory…

An Errant Editing Enzyme Promotes Tumor Suppressor Loss and Leukemia Propagation

January 3, 2019

UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.

Genetic Testing Cost Effective for Newly Diagnosed GIST

September 28, 2020

UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.

Protein-Protein Interaction Activates and Fuels Leukemia Cell Growth

December 21, 2015

Building upon previous research, scientists at University of California, San Diego School of Medicine and UC San Diego Moores Cancer report that a protein called Wnt5a acts on a pair of tumor-surface proteins, called ROR1 and ROR2, to accelerate the proliferation and spread of chronic lymphocytic leukemia (CLL) cells, the…

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