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Your search for “Therapy Target” returned 457 results

Study Identifies Protein Essential for Normal Heart Function

June 17, 2013

A study by researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences and the Department of Pharmacology at the University of California, San Diego, shows that a protein called MCL-1, which promotes cell survival, is essential for normal heart function.

Fly Toolkit Created for Investigating COVID-19 Infection Mechanisms

July 21, 2023

Researchers have created a resource for analyzing how viruses infect human cells. The fruit fly-based toolkit provides a shortcut for assessing SARS-CoV-2 genes and understanding how they interact with human proteins, offering researchers a resource for new COVID-related drug therapies.

Trained Viruses Prove More Effective at Fighting Antibiotic Resistance

June 7, 2021

Research reveals that phage viruses that undergo special evolutionary training increase their capacity to subdue bacteria. The results provide hope for the antibiotic resistance crisis, a rising threat as deadly bacteria continue to evolve to render many modern drugs ineffective.

TIME’s List of 50 Most Influential People in Health Care Includes a Real ‘Phage’ Turner

October 25, 2018

…about bacteriophages—viruses that specifically target bacteria, their name meaning “bacteria eaters—and she urged her colleagues in the School of Medicine to try them. It would be a first as a last resort. “To our knowledge, Tom was the first patient in the United States with an overwhelming, systemic infection to…

UC San Diego’s PhD Programs Dominate U.S. News and World Report’s Best Grad Schools List

March 20, 2018

As prospective graduate students across the country research course offerings and consider possible universities to attend, U.S. News & World Report has released its annual list of the nation’s top graduate programs that names professional schools and academic divisions at the University of California San Diego among the best in…

Autism Center at UC San Diego Receives $1.5 Million Gift

April 14, 2021

The UC San Diego Autism Center for Excellence has received a $1.5 million gift from Kristin Farmer, founder and chief executive officer of ACES, a company that provides services to children with autism and their families, to support the work of Karen Pierce, co-director of the Autism Center.

Extrachromosomal DNA is common in human cancer and drives poor patient outcomes

August 17, 2020

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including the University of California San Diego.

Patient First in Region to Receive New Treatment for Advanced Prostate Cancer

October 5, 2022

UC San Diego Health is the first hospital system in the region to offer a novel treatment option for patients with prostate cancer that has spread throughout the body and has not responded to other therapeutics.

Grad Students Perfect the 3-minute Pitch at Grad Slam

April 21, 2016

…again with an aggressive therapy and they go away—and then they come back. The cycle continues until loss of life.” Then she shifted to why this happens. Gliomas are mosaics of cells that can be genetically very different, she explained. So when hit with a single target-based therapy, tumor recovery…

Vinculin protein boosts function in the aging heart

June 17, 2015

…heart function as organisms age could lead to new therapy targets that address age-related heart failure.

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