May 5, 2014
With accelerating development of personalized cancer treatments matched to a patient’s DNA sequencing, proponents say frontline physicians increasingly need help to maneuver through the complex genomic landscape to find the most effective, individualized therapy.
March 1, 2021
A repurposed drug used to treat arthritis did not significantly improve the outcomes of patients with severe COVID-19 pneumonia. Tocilizumab did not significantly improve clinical status or mortality rate at 28 days for participants who received it compared to a placebo.
September 5, 2016
Using a unique computational approach to rapidly sample, in millisecond time intervals, proteins in their natural state of gyrating, bobbing, and weaving, a research team from UC San Diego and Monash University in Australia has identified promising drug candidates that may selectively combat heart disease, from arrhythmias to cardiac failure.
March 9, 2021
Bioengineers at UC San Diego and San Diego State University have discovered a key feature that allows cancer cells to break from typical cell behavior and migrate away from stiffer tissue in a tumor, shedding light on the process of metastasis and offering possible new targets for cancer therapies.
November 9, 2015
In an effort to advance research on one of the deadliest forms of cancer, University of California, San Diego School of Medicine researchers Andrew Lowy, MD, and Tannishtha Reya, PhD, have been recruited for their expertise in preclinical modeling, clinical trials and stem cell biology to join a “dream team”…
February 19, 2020
UC San Diego bioengineers developed a control system that could make CAR T-cell therapy safer and more powerful when treating cancer. By programming CAR T cells to switch on when exposed to blue light, the researchers controlled the cells to destroy skin tumors in mice without harming healthy tissue
August 9, 2023
Promising preclinical results from UC San Diego show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer’s disease.
June 6, 2016
In a meta-analysis of hundreds of clinical trials involving thousands of patients, researchers at University of California San Diego School of Medicine report that therapeutic approaches using precision medicine, which emphasizes the use of individual genetics to refine cancer treatment, showed improved response and longer periods of disease remission, even…
October 17, 2019
…Patients to Latest Cancer Therapies Using a personalized approach, Moores Cancer Center at UC San Diego Health employs genetic profiling to treat patients who have not responded to, or relapsed from, standard treatments A third occurrence of colon cancer and a failed immunotherapy clinical trial left Gordon Levine confined to…
July 29, 2015
…extremely difficult-to-treat blood cancer. The finding offers a novel target for better treating AML, and possibly other cancers, by cutting off the ability of tumors to access nearby cellular players that feed its growth.
