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Your search for “Immune System” returned 447 results

Q&A with Dr. Chip Schooley on How SARS-CoV-2 Spreads, Vaccine Trials Underway and More

August 13, 2020

…is to show your immune system what the virus would look like if you got exposed, have the immune system react to that, and become better prepared to attack the virus if you become infected. These vaccines have passed safety requirements. I would encourage those who are interested to join…

Studies Reveal How Cells Distinguish Between Disease-Causing and Innocuous Invaders

April 12, 2012

A study conducted on roundworms by biologists at UC San Diego has uncovered some important clues to answering the question of how humans and other animals are able to discriminate between disease-causing microbes and innocuous ones to rapidly respond to infections.

Single Enzyme Helps Drive Inflammation in Mice, Provides Target for New Sepsis Drugs

August 13, 2019

UC San Diego researchers discovered that removing a single enzyme in mice dramatically boosts survival from sepsis, an often fatal over-reaction of the immune system to infection. The finding provides a new and unexpected therapeutic target for new drug development.

Researchers Find a Likely Cause of Inflammatory Myofibroblastic Tumors

June 27, 2016

Researchers at University of California San Diego School of Medicine have found that a likely cause of inflammatory myofibroblastic tumors is deficiency in nonsense-mediated RNA decay (NMD), a system cells use to control which genes are activated.

Novel Cytokine Protects Mice from Colitis

August 24, 2011

Inflammatory bowel disease (IBD), which affects more than 1 million patients in North America, results from an uncontrolled immune response triggered by environmental factors, such as bacteria, in people genetically predisposed to the disorder. Ulcerative colitis, or inflammation of the lining of the colon, is one such condition.

Locking Down the Big Bang of Immune Cells

September 21, 2017

…in the development of immune cells called T cells. These areas activate a change in the 3D structure of DNA that brings together crucial elements necessary for T cell formation. This “big bang” discovery may be unfolding throughout the animal and plant kingdoms as well as aid in combating diseases…

Researchers Uncover Mechanisms behind Enigmatic Shapes of Nuclei

February 14, 2024

White blood cells known as neutrophils feature a nucleus that is structured strikingly different than most nuclei. These unique shapes permit neutrophils to travel all over the body to combat invading pathogens. Scientists have now deciphered the shapeshifting puzzle of the neutrophil nucleus.

A Deep Look into the Biology and Evolution of COVID-19

April 9, 2020

…overwhelm global health care systems; and the immense reservoir of carriers of the disease. RELATED STORY Dissecting COVID-19: Biology Professor Opens Infectious Disease Course to Public Audiences “It is estimated that there may be tenfold more asymptomatic carriers of the disease, which means that there could be over seven-and-a-half million…

Flesh-Eating Infections in Rheumatoid Arthritis Patients Spur New Discovery

August 19, 2016

…molecule that stimulates the immune system, are 300 times more likely to experience invasive Group A Streptococcal infections than patients not on the drug, according to University of California San Diego School of Medicine researchers. Their study, published August 19 in Science Immunology, also uncovers a critical new role for…

Immune Cells Anchored in Tissues Offer Unique Defenses Against Pathogens and Cancers

June 29, 2022

Researchers are expanding their understanding of unique immune “memory” cells equipped to remember malicious invaders. They developed an atlas that describes tissue-resident memory cells in diverse settings, boosting prospects for new immune defense strategies at vulnerable infection sites.

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