December 1, 2016
Previous studies identified the Hippo pathway kinases LATS1/2 as a tumor suppressor, but new research led by University of California San Diego School of Medicine scientists reveals a surprising role for these enzymes in subduing cancer immunity. The findings could have a clinical role in improving efficiency of immunotherapy drugs.
August 20, 2015
…various types of functional cells with different fates of immune rejection.
January 2, 2014
…could prevent the human immune system from rejecting the grafts derived from human embryonic stem cells, a major problem now limiting the development of human stem cell therapies. Their discovery may also provide scientists with a better understanding of how tumors evade the human immune system when they spread throughout…
July 1, 2021
Researchers at UC San Diego Health have launched a pair of clinical trials to study the immune response of COVID-19 vaccinated transplant recipients of bone marrow and solid organs, such as the heart, lung, liver and kidney.
January 28, 2021
A new study by UC San Diego biologists has revealed insights on the intricate, adaptive mechanisms of a protective system employed by the cells of mammalian immune systems. These defenses have evolved to set a type of tripwire that produces an immune response against attack from viruses.
November 6, 2017
…University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The research could lead to new therapeutic strategies for heart disease. Researchers present their findings in the Nov. 6 issue of Nature Medicine.
December 12, 2018
UC San Diego researchers join national effort to better understand human immune system as part of new Allen Institute of Immunology.
September 21, 2017
Checkpoint inhibitor-based immunotherapy has been shown to be very effective in recurrent and metastatic head and neck cancer but only in a minority of patients. University of California San Diego School of Medicine researchers may have found a way to double down on immunotherapy’s effectiveness.
July 21, 2020
Researchers investigating the ways that plants protect themselves—from insects to pathogens—have discovered an “on-off” switch that controls plant defensive mechanisms. The finding lays the groundwork for improved plant disease resistance and food stability.
December 15, 2015
Around this time every year, the flu virus infects up to one-fifth of the U.S. population and kills thousands of people, many of them elderly. A study published by Cell Press on Dec. 15 in Immunity now explains why the flu vaccine is less effective at protecting older individuals. More…
