September 20, 2023
To advance research and patient care for those suffering from lupus, William J. Wolfe and his family have donated $1.6 million to establish the Wolfe Lupus Research Fund at UC San Diego.
October 14, 2020
Treatment with a peptide that mimics the naturally occurring protein GIV prevents immune overreaction and supports a mechanism critical for survival in mouse models of sepsis and colitis, according to a UC San Diego study.
August 30, 2023
Immunologists have uncovered new approaches to enhance protection from tumors and infections. They have revealed new insights into the metabolism of specialized cells of the immune system known as tissue-resident CD8 T cells and how they could be enhanced as immune defense weapons against tumors.
July 2, 2020
…functions of our nervous system. Biologists have only recently come to understand that this is happening in many different environments, every day. Often howmicrobes like bacteria or viruses are changing the way our nervous system works is not really well understood. My lab is interested in understanding how, but also…
January 12, 2017
It’s well known that regular physical activity has health benefits, including weight control, strengthening the heart, bones and muscles and reducing the risk of certain diseases. Recently, researchers at University of California San Diego School of Medicine found how just one session of moderate exercise can also act as an…
February 22, 2016
…HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. The study, published February 22, 2016 in Nature Microbiology, identifies a new mechanism for controlling HIV replication and its interaction with the host immune…
May 13, 2024
An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study from the University of California San Diego. The treatment, composed of nanoparticles fashioned from the cowpea mosaic virus—a virus that infects black-eyed pea plants—showed remarkable…
October 26, 2021
University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.
April 11, 2022
Researchers at UC San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.
February 18, 2021
UC San Diego researchers report that individual immune response to SARS-CoV-2 may be limited by a set of variable genes that code for cell surface proteins essential for the adaptive immune system. The finding may help explain why COVID-19 immunity varies by individual.
