January 16, 2024
A vaccine for Staphylococcus aureus, one of the most common bacterial infections, would be a game changer for public health. No vaccine candidates have succeeded in clinical trials, but nobody knows why. Researchers at UC San Diego may have figured it out.
April 12, 2016
…(NIH) to establish an interdisciplinary center to define the systems biology of antibiotic resistance. The program will be led by Bernhard Palsson, PhD, Distinguished Professor of Bioengineering and Pediatrics, and Victor Nizet, MD, professor of pediatrics and pharmacy.
October 17, 2017
…for Your Child’s Developing Immune System, from 5:30 – 7:00 p.m. in Geisel Library’s Seuss Room. The UC San Diego Library talk is free to attend and open to the public. A reception and a book signing with Dr. Knight will follow. Copies of the book will be available for…
September 15, 2014
…these cancer cell glycans are capable of engaging with immune system cells and changing the latter’s response to the tumor – for good and bad.
May 14, 2020
…the foundation of our immune system create a personalized repertoire of antibodies to protect against invading pathogens. They may also shed light on why some people have a more effective immune response to an infection. “This study will be particularly helpful as dozens of groups begin testing potential COVID-19 vaccines,…
August 7, 2017
…alone wipes out macrophages, but not other types of immune cells. The macrophages’ self-sacrifice serves as an early warning of infection to the rest of the immune system.
December 18, 2012
Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth.
September 5, 2016
Biochemists at the University of California San Diego have uncovered patterns in the outer protein coat of group A Streptococcus that could finally lead to a vaccine against this highly infectious bacteria—responsible for more than 500,000 deaths a year, including toxic shock syndrome and necrotizing fasciitis or “flesh-eating disease.”
June 22, 2020
UC San Diego researchers uncovered in mice how IRE1α, a molecule involved in cells’ response to stress, determines whether macrophages promote inflammation in the tumor microenvironment. Inflammation is known to promote tumor growth, making IRE1α an attractive target for drug development.
June 22, 2014
Biologists at UC San Diego have found the “missing link” in the chemical system that enables animal cells to produce ribosomes—the thousands of protein “factories” contained within each cell that manufacture all of the proteins needed to build tissue and sustain life.
