January 24, 2017
Molecular biologists at UC San Diego have unlocked the code that initiates transcription and regulates the activity of more than half of all human genes, an achievement that should provide scientists with a better understanding of how human genes are turned on and off.
November 16, 2023
Researchers from UC San Diego have developed an easily-implemented toolkit for genomics researchers that simplifies the process of analyzing data with deep learning, a type of artificial intelligence capable of improving itself with limited user input.
March 16, 2023
UC San Diego researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS.
June 28, 2017
Using a novel molecular dynamics method capable of capturing the motion of gyrating proteins at time intervals up to one thousand times greater than previous efforts, a team led by UC San Diego researchers has identified, for the first time, the myriad structural changes that activate and drive CRISPR-Cas9, the…
August 15, 2017
Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.
December 23, 2020
UC San Diego and Ludwig Cancer Research scientists describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.
August 10, 2017
…chemical modifications in the DNA of individual neurons, giving the most detailed information yet on what makes one brain cell different from its neighbor. The novel approach enabled the team to sort neurons into subtypes and create new kinds of brain maps. The study also identifies new subtypes of neurons.
September 19, 2011
Researchers have developed a new method to sequence and analyze the dark matter of life—the genomes of thousands of bacteria species previously beyond scientists’ reach, from microorganisms that produce antibiotics and biofuels to microbes living in the human body.
March 31, 2022
An international research team, including University of California San Diego computer scientists, has published the first complete genome. The work was done by the Telomere to Telomere (T2T) consortium, and six papers describing the project will be published April 1 in a special edition of Science.
February 16, 2017
Engineering students are using DNA origami to fight cancer. Photos by David Baillot/Jacobs School of Engineering Engineering Undergraduates Use DNA Origami to Target Cancer A team of engineering students has a cancer-fighting idea up its sleeve—and the sleeve is nanoscale. The idea is based on a new cutting-edge research tool…
