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Your search for “DNA” returned 584 results

How DNA Damage Affects Golgi – The Cell’s Shipping Department

January 30, 2014

In studying the impact of DNA damage on the Golgi, a research team from the University of California, San Diego School of Medicine and the Ludwig Institute for Cancer Research have discovered a novel pathway activated by DNA damage, with important consequences for the body’s cellular response to chemotherapy.

How DNA Can Take on the Properties of Sand or Toothpaste

May 2, 2016

When does DNA behave like sand or toothpaste? When the genetic material is so densely packed within a virus, it can behave like grains of sand or toothpaste in a tube. That’s essentially what biophysicists at UC San Diego discovered when they began closely examining the physical properties of DNA…

Engineers Develop a New Biosensor Chip for Detecting DNA Mutations

June 14, 2016

…an electrical graphene chip capable of detecting mutations in DNA. Researchers say the technology could one day be used in various medical applications such as blood-based tests for early cancer screening, monitoring disease biomarkers and real-time detection of viral and microbial sequences.

Decoding the Genome’s Cryptic Language

February 24, 2017

…new tool to identify RNA-DNA interactions. The tool can provide a full account of all the RNA molecules that interact with a segment of DNA, as well as the locations of all these interactions — in just a single experiment. The research is a step toward identifying new functions and…

Relaxation Helps Pack DNA into a Virus

May 26, 2014

…out. Researchers at UC San Diego have found that DNA packs more easily into the tight confines of a virus when given a chance to relax.

Supercomputer Simulations Show How DNA Prepares Itself for Repair

June 25, 2020

Researchers from Harvard University and the University of Texas Medical Branch at Galveston recently used the Comet supercomputer at the San Diego Supercomputer Center at the University of California San Diego to uncover the novel ways in which DNA prepares itself for repair.

Biosensor Chip Detects Single Nucleotide Polymorphism Wirelessly and With Higher Sensitivity

July 9, 2018

A team led by the University of California San Diego has developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and wirelessly send the results in real time to an electronic device. The chip is at least 1,000 times more sensitive…

Program Predicts Placement of Chemical Tags that Control Gene Activity

September 22, 2014

…control the activity of genes based on sequences of DNA. They describe their analysis and report results from its application to human embryonic cells in a paper published in Nature Methods online September 21.

DNA Mismatch Repair Happens Only During A Brief Window of Opportunity

December 22, 2011

In eukaryotes – the group of organisms that include humans – a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells.

Study Reveals How Enzyme Detects Ultraviolet Light Damage

August 22, 2018

In a paper published this week in the journal PNAS, researchers at University of California San Diego School of Medicine, with colleagues in Spain and Finland, describe for the first time how one type of RNA polymerase gets stalled by DNA lesions caused by exposure to ultraviolet (UV) light.

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