July 1, 2022
Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
March 19, 2020
Scientists, including UC San Diego researchers, recently relied on supercomputer simulations to better understand the reproductive mysteries of viruses and DNA.
September 9, 2020
With the aid of artificial intelligence, UC San Diego scientists have solved a long-standing puzzle in human gene activation. The discovery described in the journal Nature could be used to control gene activation in biotechnology and biomedical applications.
March 11, 2020
From a simple blood draw, microbial DNA may reveal who has cancer and which type, even at early stages.
October 9, 2017
…based on a simple blood sample containing circulating tumor DNA.
June 15, 2022
The science behind predicting your viewing habits on Netflix could one day be used to guide doctors in managing some of the hardest-to-treat cancers, shows a study led by the University of California San Diego and University College London.
July 29, 2020
Researchers at UC San Diego School of Medicine are among the contributors to a package of 10 studies in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements project, a worldwide effort led by the NIH to understand how the human genome functions.
May 14, 2018
…that serve to package DNA inside cells. Scientists have been trying to determine how these nucleosome roadblocks clear out to allow genes to be turned on. Now, a team of scientists has identified a key factor that partially unravels nucleosomes and clears the way for genes to activate. The identification…
August 10, 2017
…be used to manipulate DNA. In 2016, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9. In a study published August 10 in Cell, the team took RCas9 a step further: they corrected molecular mistakes…
December 13, 2023
Researchers from UC San Diego have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.
