Global Regulator of mRNA Editing Found
February 6, 2014
…protein that broadly regulates how genetic information transcribed from DNA to messenger RNA (mRNA) is processed and ultimately translated into the myriad of proteins necessary for life.
Your search for “DNA” returned 600 results
Tethering of Shattered Chromosomal Fragments Paves Way for New Cancer Therapies
June 15, 2023
UC San Diego scientists discover shattered chromosomal fragments are tethered together during cell division before being rearranged; destroying the tether may help prevent cancerous mutations
Express Yourself: How Zygotes Sort Out Imprinted Genes
February 16, 2012
Researchers at the Ludwig Institute for Cancer Research, the University of California, San Diego School of Medicine and the Toronto Western Research Institute peel away some of the enduring mystery of how zygotes or fertilized eggs determine which copies of parental genes will be used or ignored.
A New Map Reveals the Complicated World in Which Cells Seek to Repair Damaged DNA
May 22, 2023
UC San Diego scientists develop an interactive software that enables scientists to better investigate the DNA damage response.
New Technique Could Expand Number of Diseases Detected by Noninvasive Prenatal Testing
November 9, 2015
Researchers at the University of California, San Diego School of Medicine developed a method to expand the types of chromosomal abnormalities that noninvasive prenatal testing (NIPT) can detect. The study, published November 9 by Proceedings of the National Academy of Sciences, uses a semiconductor sequencing platform to identify small chromosomal…
UC San Diego Computer Scientist Plays Major Role in $25M Cancer Grand Challenges Project
June 16, 2022
Computer scientist Vineet Bafna is part of a team of world-class researchers that has been awarded a five-year, $25 million grant to learn how the destructive genetic lesion extrachromosomal DNA (ecDNA) influences numerous cancers and to identify possible therapies.
Byproducts of ‘Junk DNA’ Implicated in Cancer Spread
August 15, 2018
UC San Diego biologists and their colleagues have revealed that enhancer RNAs play a significant role in cancer dissemination. The researchers found that eRNAs have a direct role in the activation of genes that are important for tumor development. This role is facilitated by the ability of eRNAs to directly…
A Novel COVID-19 Vaccine Using Modified Bacterial DNA
July 21, 2022
UC San Diego researchers describe a different way to build a COVID-19 vaccine, one that would, in theory, remain effective against new and emerging variants and could be taken as a pill, by inhalation or other delivery methods.
Joint Resolution: A Link Between Huntington’s Disease and Rheumatoid Arthritis
May 15, 2018
Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common autoimmune disease that affects more than 1.3 million Americans.
Extrachromosomal DNA is common in human cancer and drives poor patient outcomes
August 17, 2020
The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including the University of California San Diego.
