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Your search for “DNA Sequencing” returned 243 results

Scientists Find New Way to Map Differences in the Brain

August 10, 2017

…chemical modifications in the DNA of individual neurons, giving the most detailed information yet on what makes one brain cell different from its neighbor. The novel approach enabled the team to sort neurons into subtypes and create new kinds of brain maps. The study also identifies new subtypes of neurons.

New Computer Program ‘Learns’ to Identify Mosaic Mutations That Cause Disease

January 2, 2023

UC San Diego researchers describe a method for teaching a computer how to spot complex “mosaic mutations” using an artificial intelligence approach termed “deep learning.”

SDSC Supercomputers, CIPRES Gateway Help Define New “Tree of Life”

April 25, 2016

An outline for a new tree of life, depicting the evolution of life on this planet that included more than 1,000 new types of bacteria and Archaea lurking in the Earth’s nooks and crannies, was made possible with the help of supercomputing resources and a phylogenetics “gateway” created at the…

UC San Diego Scientists Part of Special Package of Studies Describing Human Genome

July 29, 2020

Researchers at UC San Diego School of Medicine are among the contributors to a package of 10 studies in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements project, a worldwide effort led by the NIH to understand how the human genome functions.

Microbial DNA in Patient Blood May be Tell-Tale Sign of Cancer

March 11, 2020

From a simple blood draw, microbial DNA may reveal who has cancer and which type, even at early stages.

Un-junking Junk DNA

November 12, 2013

A study led by researchers at the University of California, San Diego School of Medicine shines a new light on molecular tools our cells use to govern regulated gene expression.

SDSC Assists in Whole-Genome Sequencing Analysis Under Collaboration with Janssen

March 20, 2014

A recent whole-genome sequencing (WGS) analysis project supported by the San Diego Supercomputer Center (SDSC) at the University of California, San Diego has demonstrated the effectiveness of innovative applications of “flash” memory technology to rapidly process large data sets that are pervasive throughout human genomics research.

Enzymes Can’t Tell Artificial DNA From the Real Thing

December 13, 2023

Researchers from UC San Diego have come one step closer to unlocking the potential of synthetic DNA, which could help scientists develop never-before-seen proteins in the lab.

Breaking Bad: How Shattered Chromosomes Make Cancer Cells Drug-Resistant

December 23, 2020

UC San Diego and Ludwig Cancer Research scientists describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.

Blood Biopsy Reveals Unique, Targetable Genetic Alterations in Patients with Rare Cancer

August 15, 2017

Using fragments of circulating tumor DNA in blood, University of California San Diego School of Medicine researchers were able to identify theoretically targetable genetic alterations in 66 percent of patients with cancer of unknown primary (CUP), a rare disease with seven to 12 cases per 100,000 people each year.

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