December 9, 2019
Scientists have found the most effective CRISPR shield ever discovered in viruses. They discovered a remarkable new strategy that some bacteria-killing viruses, or phages, employ: after they infect bacteria, these phages construct an impenetrable “safe room” inside of their host.
April 8, 2021
An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable number tandem repeats that actively regulate gene expression. In a Nature Communications paper, the researchers provide new insights into this understudied mechanism
October 14, 2013
Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called “master regulators” read the genome, and consequently turn genes on and off.
July 27, 2023
UC San Diego scientists debut Greengenes2, a massive reference database that could be used to reconcile years of microbiome studies.
February 27, 2018
A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing…
July 1, 2022
Scientists have developed a CRISPR-based technology that could offer a safer approach to correcting genetic defects. The new “soft” CRISPR system makes use of natural DNA repair machinery, providing a foundation for novel gene therapy strategies with the potential to cure genetic diseases.
June 13, 2012
…of Medicine reports that the new technology of exome sequencing is not only a promising method for identifying disease-causing genes, but may also improve diagnoses and guide individual patient care.
June 15, 2022
The science behind predicting your viewing habits on Netflix could one day be used to guide doctors in managing some of the hardest-to-treat cancers, shows a study led by the University of California San Diego and University College London.
February 16, 2012
Researchers at the Ludwig Institute for Cancer Research, the University of California, San Diego School of Medicine and the Toronto Western Research Institute peel away some of the enduring mystery of how zygotes or fertilized eggs determine which copies of parental genes will be used or ignored.
February 4, 2019
Researchers at UC San Diego and Arizona State University have received $1.7 million in funding from The Michael J. Fox Foundation for Parkinson’s Research to launch a multi-year effort to identify blood-based biomarkers of Parkinson’s disease, which could improve care and accelerate new treatments.
