Science & Environment

Research

The Latest

New Way to Target – And Kill – Proliferating Tumors

Researchers at the University of California, San Diego School of Medicine and the UC San Diego Moores Cancer Center have identified a new drug discovery approach enabling the destruction of the most highly proliferative tumors. The discovery, published in the November 13 online issue of the journal Nature Medicine, points to an effective, alternative method for killing fast-growing cancer cells without causing some of the negative effects of current therapies.

SDSC’s Gordon Ranks Among Top 50 Fastest Supercomputers in the World

Gordon, a unique data-intensive supercomputer using flash-based memory that will enter production in January at the San Diego Supercomputer Center (SDSC) at the University of California, San Diego, made its debut as the 48th fastest supercomputer in the world, according to the latest Top500 list.

Knocking Out Key Protein in Mice Boosts Insulin Sensitivity

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

Non-Coding RNA Relocates Genes When It’s Time To Go To Work

Cells develop and thrive by turning genes on and off as needed in a precise pattern, a process known as regulated gene transcription. In a paper published in the November 9 issue of the journal Cell, researchers at the University of California, San Diego School of Medicine say this process is even more complex than previously thought, with regulated genes actually relocated to other, more conducive places in the cell nucleus.

Kawasaki Disease Linked to Wind Currents

Kawasaki Disease (KD) is a severe childhood disease that many parents, even some doctors, mistake for an inconsequential viral infection. In fact, if not diagnosed or treated in time, it can lead to irreversible heart damage. After 50 years of research, including genetic studies, scientists have been unable to pinpoint the cause of the disease.

Neurological Disorder Impacts Brain Cells Differently

In a paper published in the November 9 issue of The Journal of Neuroscience, researchers at the University of California, San Diego School of Medicine and University of Washington describe in deeper detail the pathology of a devastating neurological disorder, but also reveal new cellular targets for possibly slowing its development.