March 20, 2017
…allowing researchers to develop drugs that will selectively kill them. This is called “synthetic lethality” because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published…
June 19, 2012
Strains of bacteria able to resist multiple antibiotics pose a growing threat to public health, yet the means by which resistance quickly emerges aren’t well understood.
January 22, 2020
New research findings, published in Nature, by UC San Diego Professor of Chemistry and Biochemistry Akif Tezcan offer a protein architecture that pushes the boundaries of synthetic protein design past what is considered state-of-the-art.
September 8, 2022
…to celebrate the building’s designation as a historical site by the American Physical Society (APS). Mayer Hall, after all, was named after famed theoretical physicist Maria Goeppert Mayer—the second woman ever to win the Nobel Prize in physics. It was also the birthplace of metamaterials which, among other things, have…
February 16, 2017
…BIOMOD 2017 competition—a molecular design competition for undergraduates. Researchers have already proven that DNA origami works by folding the genetic material into shapes such as stars, smiley faces—and even a bunny. However, the UC San Diego students are not folding DNA for aesthetics alone. They are breaking the double-stranded DNA…
October 31, 2022
Computational chemistry affects everyday life more than most people might realize. It is used to develop drugs to treat diseases, generate data for environmental clean-up purposes, design solar energy technology, improve batteries, create enzymes to break down plastics and more.
July 18, 2016
Biochemists at the University of California San Diego have developed artificial cell membranes that grow and remodel themselves in a manner similar to that of living mammalian cells.
October 20, 2015
…of cancer. This important drug has now been shown to play an unexpected role in blocking one of the pathways most commonly involved in driving the growth of cancers, according to a recent study by researchers at the San Diego Supercomputer Center (SDSC) as well as the university’s Moores Cancer…
October 30, 2015
…search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half. The study is published October 30 by Oncotarget.
July 19, 2012
…Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.
