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Your search for “designer drugs” returned 446 results

DNA Treatment Could Delay Paralysis That Strikes Nearly All Patients with ALS

March 16, 2023

UC San Diego researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ALS.

Biologists Engineer Algae to Make Complex Anti-Cancer ‘Designer’ Drug

December 10, 2012

…algae to produce a complex and expensive human therapeutic drug used to treat cancer. Their achievement opens the door for making these and other “designer” proteins in larger quantities and much more cheaply than can now be made from mammalian cells.

RNA-Based Drugs Give More Control Over Gene Editing

November 16, 2015

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University…

UC San Diego Biophysicists Examine Development of Antibiotic Resistance

December 5, 2013

…antibiotics and developing new drugs against bacteria already resistant to conventional drug treatments. But understanding how bacteria grow and evolve drug resistance could also help stop its spread by allowing scientists to target the process of evolution itself. “Understanding how bacteria harboring antibiotic resistance grow in the presence of antibiotics…

SDSC Team Models Potential SARS-CoV2 Protease Inhibitors for COVID-19

December 1, 2020

A team of SDSC researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19

Clinical Trial Evaluates Synthetic Cannabinoid as Brain Cancer Treatment

September 25, 2012

Researchers at University of California, San Diego Moores Cancer Center are evaluating the safety and tolerability of a synthetic cannabinoid called dexanabinol (ETS2101). Delivered as a weekly intravenous infusion, the drug is being tested in patients with all forms of brain cancer, both primary and metastatic.

A New Approach to Faster Anticancer Drug Discovery

March 13, 2012

Tracking the genetic pathway of a disease offers a powerful, new approach to drug discovery, according to scientists at the University of California, San Diego School of Medicine who used the approach to uncover a potential treatment for prostate cancer, using a drug currently marketed for congestive heart failure.

Discovery Provides Blueprint for New Drugs That Can Inhibit Hepatitis C Virus

March 19, 2012

Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing. Hepatitis C is a chronic infectious disease that affects some 170 million people worldwide and causes…

Good Vibrations: Using Light-Heated Water to Deliver Drugs

April 1, 2014

Researchers from the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, in collaboration with materials scientists, engineers and neurobiologists, have discovered a new mechanism for using light to activate drug-delivering nanoparticles and other targeted therapeutic substances inside the body.

Don Cleveland Wins a Trifecta of Recognition

January 31, 2023

In the span of just a few weeks, Don Cleveland, a leading researcher in the study of neurodegenerative diseases like ALS and Alzheimer’s, has received three major awards.

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