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Your search for “Therapy Target” returned 457 results

Protein May Be Key to Psoriasis and Wound Care

June 21, 2012

Psoriasis is an autoimmune disorder in which skin cells proliferate out of control. For some hard-to-heal wounds, the problem is just the opposite: Restorative skin cells don’t grow well or fast enough. In a paper published in the June 21, 2012 issue of Immunity, researchers at the University of California,…

Bioinformatics Breakthrough: High Quality Transcriptome from as Few as Fifty Cells

October 24, 2013

Bioengineers from the University of California, San Diego have created a new method for analyzing RNA transcripts from samples of 50 to 100 cells. The approach could be used to develop inexpensive and rapid methods for diagnosing cancers at early stages, as well as better tools for forensics, drug discovery…

Novel Phage Therapy Saves Patient with Multidrug-Resistant Bacterial Infection

April 25, 2017

…Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages — viruses that target and consume specific strains of bacteria — to treat a patient near death from a multidrug-resistant bacterium.

One-Time Treatment Generates New Neurons, Eliminates Parkinson’s Disease in Mice

June 24, 2020

UC San Diego researchers have discovered that a single treatment to inhibit a gene called PTB in mice converts native astrocytes, brain support cells, into neurons that produce the neurotransmitter dopamine. As a result, the mice’s Parkinson’s disease symptoms disappear.

New Cancer Immunotherapy Approach Turns Immune Cells into Tiny Anti-Tumor Drug Factories

December 4, 2018

In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs.

T Cells Can Activate Themselves to Fight Tumors

May 8, 2023

UC San Diego scientists find an auto-signaling mechanism driving the T cell anti-tumor response; findings may inspire new cancer therapeutics and biomarkers.

Alcohol Use Linked to Lower Connectivity in Brain Areas that Process Emotions

February 8, 2022

People at risk of developing alcohol use disorder show lower functional connectivity between brain regions involved in processing facial expressions. Future psychoeducation programs focused on improving social and emotional processing may help prevent alcohol use disorder.

UC San Diego Researchers Develop Sensors to Detect and Measure Cancer’s Ability to Spread

December 5, 2018

University of California San Diego School of Medicine researchers engineered sensors to detect and measure the metastatic potential of single cancer cells. Metastasis is attributed as the leading cause of death in people with cancer.

Spotlight on Faculty Research: Stem Cell

November 14, 2011

…cells aimed at developing therapies for heart failure and cardiac pacemaker dysfunction. To repair of human heart, it is important to study human cardiac progenitors and to define pathways required to grow and differentiate them utilizing human cells as a model experimental system. Evans’ lab will create special lines of…

Researchers Block Pathway to Cancer Cell Replication

July 3, 2012

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a time, only to later begin cloning, resulting in a return and metastasis of the disease.…

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