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Your search for “Therapy Target” returned 457 results

Dysfunction in Neuronal Transport Mechanism Linked to Alzheimer’s Disease

October 12, 2016

Researchers at University of California San Diego School of Medicine have confirmed that mutation-caused dysfunction in a process cells use to transport molecules within the cell plays a previously suspected but underappreciated role in promoting the heritable form of Alzheimer’s disease (AD), but also one that might be remedied with…

Does Blood Plasma from COVID-19 Survivors Help Patients Infected with Novel Coronavirus?

July 9, 2020

Researchers at University of California San Diego School of Medicine and UC San Diego Health have launched a clinical trial to assess the safety and efficacy of convalescent plasma (CP) to prevent COVID-19 after a known exposure to the virus.

Researchers Discover Specific Tumor Environment That Triggers Cells to Metastasize

November 21, 2017

A team of bioengineers and bioinformaticians at the University of California San Diego have discovered how the environment surrounding a tumor can trigger metastatic behavior in cancer cells. Specifically, when tumor cells are confined in a dense environment, the researchers found that they turn on a specific set of genes…

Bioengineering Alumnus on COVID-19 Antiviral Pill Development Team

February 24, 2022

…effective dosage of new therapies in development. Most recently, Boras was part of the team at Pfizer that developed the Paxlovid COVID-19 antiviral pill, the first oral antiviral treatment for COVID-19 to receive FDA emergency use authorization. Boras shared what led him to UC San Diego, how his graduate degree…

Splicing Deregulation Detected and Targeted in Type of Childhood Leukemia

March 7, 2023

UC San Diego researchers delve deep into the unknown cause of pediatric acute myeloid leukemia to identify a gene splicing dysregulation and potential target for treating the disease, which often becomes treatment-resistant.

Students Propose Solutions to Critical Health Issues at Annual Hackathon

March 23, 2017

From virtual reality to crowdsourcing ideas, participants at UC Health Hack 2017 combined creativity and problem-solving to create projects addressing critical issues in health systems and global health. The 181 participants focused on one of two tracks: health care delivery or refugee health.

Created Line of Spinal Cord Neural Stem Cells Shows Diverse Promise

August 6, 2018

Researchers at University of California San Diego School of Medicine report that they have successfully created spinal cord neural stem cells (NSCs) from human pluripotent stem cells (hPSCs) that differentiate into a diverse population of cells capable of dispersing throughout the spinal cord and can be maintained for long periods…

Cancer Cells Co-opt Immune Response to Escape Destruction

December 18, 2012

Researchers at the University of California, San Diego School of Medicine report that tumor cells use stress signals to subvert responding immune cells, exploiting them to actually boost conditions beneficial to cancer growth.

UC San Diego Moores Cancer Center’s J. Silvio Gutkind Joins National Academy of Medicine

October 21, 2019

J. Silvio Gutkind elected to National Academy of Medicine for his contributions to the understanding of cancer signaling networks and pioneering the study of the PIK3CA-mTOR signaling circuitry in head and neck cancer.

New Reprogramming Method Makes Better Stem Cells

July 2, 2014

…cells and could ultimately lead to improved stem cell therapies.

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