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Your search for “Cancer Mutations” returned 226 results

Novel Imaging Model Helps Reveal New Therapeutic Target for Pancreatic Cancer

June 6, 2016

…most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. In a new study, researchers at University of California San Diego School of Medicine and Moores Cancer Center, together with colleagues at Keio University, the University of Nebraska and Ionis Pharmaceuticals describe an…

Proposed Drug May Reverse Huntington’s Disease Symptoms

June 20, 2012

With a single drug treatment, researchers at the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine can silence the mutated gene responsible for Huntington’s disease, slowing and partially reversing progression of the fatal neurodegenerative disorder in animal models.

New Genetic Method Promises to Advance Gene Research and Control Insect Pests

March 19, 2015

…San Diego have developed a new method for generating mutations in both copies of a gene in a single generation that could rapidly accelerate genetic research on diverse species and provide scientists with a powerful new tool to control insect borne diseases such as malaria as well as animal and…

Synthetic Biologists Extend Functional Life of Cancer-Fighting Circuitry in Microbes

September 5, 2019

Bioengineers and biologists at the University of California San Diego have developed a method to significantly extend the life of gene circuits used to instruct microbes to do things such as produce and deliver drugs, break down chemicals and serve as environmental sensors.

New Gene Fusions and Mutations Linked to Gastrointestinal Stromal Tumors

December 15, 2016

…have identified specific gene mutations linked to gastrointestinal stromal tumors (GIST), which primarily occur in the stomach or small intestine, but 10 to 15 percent of adult GIST cases and most pediatric cases lack the tell-tale mutations, making identification and treatment difficult. Researchers at University of California San Diego School…

Genetic Variation Explains Racial Disparity in Esophageal Cancer Cases

September 22, 2022

Researchers at UC San Diego have used artificial intelligence-guided tools to pinpoint both a specific type of immune cell as the driver of esophageal cancer and a specific genetic variation that acts as a protective factor in African Americans.

What Happens When We Sunburn

July 9, 2012

The biological mechanism of sunburn – the reddish, painful, protective immune response from ultraviolet (UV) radiation – is a consequence of RNA damage to skin cells, report researchers at the University of California, San Diego School of Medicine and elsewhere in the July 8, 2012 Advance Online Publication of Nature…

UC San Diego Cancer Scientists Named to First Class of AACR Fellows

March 27, 2013

…the American Association for Cancer Research Academy, created to recognize researchers whose scientific contributions have propelled significant innovation and progress against cancer. The entire class consists of 106 individuals, to celebrate the 106 year anniversary of AACR, the world’s first and largest professional organization dedicated to advancing cancer research.

Culture Clash: How Stem Cells Are Grown Affects Their Genetic Stability

February 25, 2015

Writing in the February 25 online issue of the journal PLOS ONE, researchers at University of California, San Diego School of Medicine, with collaborators from The Scripps Research Institute (TSRI), have definitively shown for the first time that the culture conditions in which stem cells are grown and mass-produced can…

Antibody Breaks Leukemia’s Hold, Providing New Therapeutic Approach

October 27, 2016

…(AML) is an aggressive cancer known for drug resistance and relapse. In an effort to uncover new treatment strategies, researchers at University of California San Diego School of Medicine and Moores Cancer Center discovered that a cell surface molecule known as CD98 promotes AML. The study also shows that inhibiting…

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