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Your search for “Cancer Mutations” returned 226 results

Signaling Molecule Crucial to Stem Cell Reprogramming

November 20, 2014

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments.

Exposing Cancer’s Metabolic Addictions

April 24, 2019

University of California San Diego School of Medicine researchers and collaborators describe a new set of “rules” that predict how the tissue of origin influences critical aspects of the genetic makeup of tumors, with potentially important therapeutic implications.

Personalizing Precision Medicine with Combination Therapies Improves Outcomes in Cancer

April 22, 2019

University of California San Diego School of Medicine researchers found that treating patients with personalized precision medicine that combined therapies to target multiple alterations improved outcomes in patients with therapy resistant cancers.

Ovarian Cancer-Specific Markers Set the Stage for Early Diagnosis, Personalized Treatments

May 25, 2015

…of Medicine and Moores Cancer Center have now identified six mRNA isoforms (bits of genetic material) produced by ovarian cancer cells but not normal cells, opening up the possibility that they could be used to diagnose early-stage ovarian cancer. What’s more, several of the mRNA isoforms code for unique proteins…

May 13 SPARK Gala Ignites New Discoveries in the Fight Against Cancer

April 19, 2017

…13 to celebrate recent advances in the fight against cancer and spur on new discoveries. Proceeds from the event will benefit research and patient care at Moores Cancer Center at UC San Diego Health, including the Center for Personalized Cancer Therapy.

Looking Beyond DNA to See Cancer with New Clarity

September 30, 2021

In three Science papers, UC San Diego and UC San Francisco researchers mapped out how hundreds of gene mutations involved in cancer affect the discrete groups of proteins that are the ultimate actors behind the disease. The work points the way to identifying new precision treatments.

Genetic Testing Cost Effective for Newly Diagnosed GIST

September 28, 2020

UC San Diego School of Medicine researchers reported that genetic testing is cost-effective and beneficial for newly diagnosed patients with metastatic gastrointestinal stromal tumors (GIST), a rare type of cancer.

We Need You: Join All of Us to Advance Precision Medicine

May 10, 2018

…care at five different cancer centers hoping for a different outcome. At one center, he was treated with the only currently available therapy for metastatic basal cell carcinoma. It was ineffective. How to participate To learn more about the All of Us Research Program and how to join, please visit…

$12.7M Grant to Establish New Center to Investigate Genetic Basis of Autism and Schizophrenia

October 10, 2024

Funded by a California Institute for Regenerative Medicine grant, researchers in the UC San Diego Verge Center aim to uncover the genetic mechanisms behind neuropsychiatric disorders.

How Loss of Single Gene Fuels Deadly Childhood Brain Cancer

September 10, 2020

UC San Diego researchers describe how the functional loss of a single gene negatively impacts neural development and promotes the growth of a particularly deadly form of pediatric brain cancer.

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