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Your search for “Cancer Mutations” returned 226 results

UCSD Study Shows Why Protein Mutations Lead to Familial Form of Parkinson’s Disease

January 21, 2015

Researchers at the San Diego Supercomputer Center (SDSC) at the University of California, San Diego, have shown for the first time why protein mutations lead to the familial form of Parkinson’s disease

Upending a Cancer Dogma

July 2, 2014

Researchers at the University of California, San Diego School of Medicine say a protein essential to regulating cell cycle progression – the process of cell division and replication – activates a key tumor suppressor, rather than inactivating it as previously thought.

Melanoma of the Eye Caused by Two Gene Mutations

May 29, 2014

Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA-approved drug.

Technique to Study How Proteins Bind to DNA is Easily Misused; New Study Offers Solution

September 13, 2024

Spike-in normalization helps molecular biologists ensure the accuracy of their results, but the technique is easily misused. New study suggests new guidelines for use of this valuable technique.

Opposite Effect: Protein Widely Known to Fight Tumors Also Boosts Cancer Growth

January 31, 2019

UC San Diego researchers studying p53, the heralded cancer-fighting “guardian of the genome,” found that the human protein also plays a role in promoting tumors, in addition to suppressing them.

Stress-Tolerant Cells Drive Tumor Initiation in Pancreatic Cancer

January 17, 2023

UC San Diego scientists discover a molecular pathway critical to the initiation of pancreatic tumors. The findings may inspire new chemotherapeutic drugs targeting early stages of tumor formation and spread

Potential Drug Target for Difficult-To-Treat Breast Cancer: RNA-Binding Proteins

July 2, 2021

UC San Diego studies using human cell lines and tumors grown in mice provide early evidence that inhibiting RNA-binding proteins, a previously overlooked family of molecules, might provide a new approach for treating some cancers.

CIRM Funds Six UC San Diego Stem Cell Researchers

September 6, 2012

The governing board of the California Institute for Regenerative Medicine (CIRM) has announced that six investigators from the University of California, San Diego Stem Cell Research program have received a total of more than $7 million in the latest round of CIRM funding. This brings UC San Diego’s total to…

UC San Diego, UC San Francisco Launch New Cancer Cell Mapping Initiative

January 29, 2015

…have launched an ambitious new project – dubbed the Cancer Cell Map Initiative or CCMI – to determine how all of the components of a cancer cell interact.

New Clinic Matches Patients with Cancer to Latest Precision Immunotherapy Treatments

October 17, 2019

New Precision Immunotherapy Therapy clinic at Moores Cancer Center at UC San Diego Health matches patients using genetic profiling to personalized cancer treatment plans.

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