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Your search for “Cancer Mutations” returned 226 results

Understudied Mutations Have Big Impact on Gene Expression

April 8, 2021

An international team of researchers led by computer scientists at the University of California San Diego have identified 163 variable number tandem repeats that actively regulate gene expression. In a Nature Communications paper, the researchers provide new insights into this understudied mechanism

Tumor Reasons Why Cancers Thrive in Chromosomal Chaos

October 26, 2021

University of California San Diego researchers describe how a pair of fundamental genetic and cellular processes — aneuploidy and unfolded protein response — are exploited by cancer cells to promote tumor survival and growth.

Researchers Find a New Way to Identify and Target Malignant Aging in Leukemia

August 26, 2016

…of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout…

UC San Diego Health Joins Precision Medicine Initiative to Tackle Pancreatic Cancer

October 4, 2016

Physician-scientists with Moores Cancer Center at UC San Diego Health have been leading the way in pancreatic cancer care by investigating new therapies as well as offering innovative clinical trials and the latest treatments with a personalized medicine approach. This expertise led to the selection of Moores Cancer Center as…

Study: Endometrial Cancer Treatment Has Significant Results

March 27, 2023

Researchers at UC San Diego School of Medicine and Moores Cancer Center at UC San Diego Health examined a new treatment approach for endometrial cancer.

Chatter Between Cell Populations Drives Progression of Gastrointestinal Tumors

February 18, 2021

Researchers at University of California San Diego School of Medicine identified new therapeutic targets for gastrointestinal stromal tumors (GISTs) that could lead to new treatment options for patients.

Too Much of a Good Thing May Lead to Too Much of a Liver As Well

February 24, 2020

UC San Diego researchers suggest that prolonged exposure to a pair of antioxidant proteins may contribute to enlargement of the liver and fatty liver diseases.

Strauss Family Gives UC San Diego $1 Million to Help Develop a Cancer Vaccine

October 17, 2017

…the doctors at Moores Cancer Center at UC San Diego Health. When their daughter’s cancer reappeared, it was the first place they turned for help. Because of their experience and trust in the medical and research staff, the couple recently donated $1 million to the University of California San Diego…

Blocking Known Cancer Driver Unexpectedly Reveals a New Tumor-Promoting Pathway

May 17, 2016

…pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San Diego School of Medicine researchers found that an alternative pathway immediately emerges when ERK1/2 is halted, thus allowing tumor cell proliferation to continue.

Don Cleveland Wins a Trifecta of Recognition

January 31, 2023

In the span of just a few weeks, Don Cleveland, a leading researcher in the study of neurodegenerative diseases like ALS and Alzheimer’s, has received three major awards.

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