Skip to main content

Your search for “Cancer Mutations” returned 226 results

Oncogene Mutation Hijacks Splicing Process to Promote Growth and Survival

May 31, 2013

…the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine – has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that…

How Breast Cancer Usurps the Powers of Mammary Stem Cells

August 11, 2014

…of California, San Diego School of Medicine and Moores Cancer Center have found that mammary stem cells associated with the pregnant mammary gland are related to stem cells found in breast cancer.

Study Uses Precision Medicine to Speed Drug Testing for Pancreatic Cancer

April 15, 2021

Moores Cancer Center at UC San Diego Health is among the few clinical trial sites in the U.S. for the Pancreatic Cancer Action Network’s (PanCAN) newly created Precision Promise, the first large-scale precision medicine trial designed to transform outcomes for patients with pancreatic cancer.

UC San Diego Study Points to Virus-Related Acceleration in Some Cancers

March 14, 2019

A new paper by UC San Diego researchers hypothesizes a possible link between cancer-causing viruses.

Hope for Our Zebra

May 1, 2023

When alumni Michaelle Jinette and Kevin Witt’s fourth son Tristan was diagnosed with the rare KCNH1 genetic mutation, the couple raised money, collaborated with scientific partners, and initiated rare disease research on behalf of their child and the 50 others like him in the world.

Antibody Drug Conjugates May Help Personalize Radiotherapy for Patients with Cancer

October 4, 2016

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

Genetic Variations that Boost PKC Enzyme Contribute to Alzheimer’s Disease

May 10, 2016

In Alzheimer’s disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons. Now, researchers at University of California San Diego School of Medicine and Harvard Medical School have found that the enzyme Protein Kinase C (PKC) alpha is necessary for amyloid beta to damage neuronal connections.…

UC San Diego Researcher Receives $6.25 Million Grant

October 14, 2013

The Leukemia & Lymphoma Society has awarded Thomas J. Kipps, MD, PhD, Distinguished Professor of Medicine at the University of California, San Diego School of Medicine, with a 5-year, $6.25 million Specialized Center of Research program grant to support research on chronic lymphocytic leukemia.

DNA Mismatch Repair Happens Only During A Brief Window of Opportunity

December 22, 2011

In eukaryotes – the group of organisms that include humans – a key to survival is the ability of certain proteins to quickly and accurately repair genetic errors that occur when DNA is replicated to make new cells.

Body’s Own Gene Editing System Generates Leukemia Stem Cells

June 9, 2016

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers at University of California San Diego School of Medicine have now unraveled how pre-leukemic…

Category navigation with Social links