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Your search for “Cancer Mutations” returned 220 results

In Cells, UV-Emitting Nail Polish Dryers Damage DNA and Cause Mutations

January 17, 2023

The ultraviolet nail polish drying devices used to cure gel manicures may pose more of a public health concern than previously thought. Researchers at UC San Diego studied these UV light-emitting devices, and found that their use leads to cell death and cancer-causing mutations in human cells.

Mutant Gene Found to Fuel Cancer-Promoting Effects of Inflammation

October 23, 2017

…to chronic inflammation and cancer. Through large-scale genomic analyses, they discovered that “mutant p53” amplifies the impact of inflammation, leading to increases in cancer. Thus, rather than fighting tumor growth, mutant forms of p53 appear to be tapping into the body’s immune response system to fuel pro-inflammatory responses that increase…

How a Virus Causes Chromosomal Breakage, Leading to Cancer

April 13, 2023

UC San Diego researchers describe for the first time how the Epstein-Barr virus exploits genomic weaknesses to cause cancer while reducing the body’s ability to suppress it.

Women Needed to Contribute to WISDOM for Breast Cancer Screening

November 6, 2017

…medical centers, including Moores Cancer Center at UC San Diego Health, have joined together to recruit 100,000 women in California to be part of WISDOM: a clinical trial to uncover whether annual mammograms are the best way to screen for breast cancer, or whether a more personalized approach could deliver…

Brain Cancer Cells Hide While Drugs Seek

December 5, 2013

…the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.

Netflix-Style Algorithm Builds Blueprint of Cancer Genomes

June 15, 2022

The science behind predicting your viewing habits on Netflix could one day be used to guide doctors in managing some of the hardest-to-treat cancers, shows a study led by the University of California San Diego and University College London.

New Combination Treatment Strategy to “Checkmate” Glioblastoma

May 8, 2015

Therapies that specifically target mutations in a person’s cancer have been much-heralded in recent years, yet cancer cells often find a way around them. To address this, researchers at University of California, San Diego School of Medicine and Moores Cancer Center identified a promising combinatorial approach to treating glioblastomas, the…

DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

October 1, 2017

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies.

Breaking Bad: How Shattered Chromosomes Make Cancer Cells Drug-Resistant

December 23, 2020

UC San Diego and Ludwig Cancer Research scientists describe how a phenomenon known as “chromothripsis” breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth.

UC San Diego Moores Cancer Center Launches Bold Campaign to Personalize Cancer Treatment

September 17, 2012

UC San Diego Moores Cancer Center launched a bold plan today, aimed at personalizing cancer treatment. The “My Answer to Cancer” team of oncologists, bioinformaticians, pathologists and geneticists pledges to “sequence” or analyze the DNA of large numbers of patients with cancer in order to match each patient to the…

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