Science & Environment

Research

The Latest

New Gene Fusions and Mutations Linked to Gastrointestinal Stromal Tumors

In recent years, researchers have identified specific gene mutations linked to gastrointestinal stromal tumors (GIST), which primarily occur in the stomach or small intestine, but 10 to 15 percent of adult GIST cases and most pediatric cases lack the tell-tale mutations, making identification and treatment difficult. Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified new gene fusions and mutations associated with this subset of GIST patients.

UC San Diego Research Awarded $3.8 Million for Critical, Innovative Work

University of California San Diego researchers are leading three separate research projects, each involving faculty from across the UC system. A total of $3.79 million in grants from the University of California Multicampus Research and Programs Initiatives has been awarded to fund the work.

Art’s Content: Jacobs Medical Center Captures Curative Power of Creativity

Modern hospitals are designed to aid healing in every possible space, from operating rooms and recovery areas to cafeterias and lobbies. One way is through art, and the new Jacobs Medical Center at UC San Diego Health reflects this with an extraordinary collection of paintings, photographs, sculptures, and other mediums, by renowned artists that are featured on every floor and inside every patient room throughout the 10-story hospital.

Engineers Develop a New Non-Invasive Method to Detect Infections in Prostheses

Engineers at the University of California San Diego have developed a new non-invasive method to detect infections in prostheses used for amputees, as well as for knee, hip and other joint replacements. The method, which is at the proof of concept stage, consists of a simple imaging technique and an innovative material to coat the prostheses.

Unexpected Activity of Two Enzymes Helps Explain Why Liver Cancer Drugs Fail

Researchers at University of California San Diego School of Medicine have discovered that lack of two types of enzymes can lead to liver disease and cancer in mice. In human liver tumors, they found that deficiencies in these two enzymes, Shp2 and Pten, are associated with poor prognosis. The study, published December 13 by Cell Reports, provides a new understanding of liver cancer development, new therapeutic approach and new mouse model for studying the disease.

From round to square

Researchers at the University of California San Diego for the first time have revealed why the shape of the feather shaft changes from round to square when it’s put under stress in a paper published in recent issue of Advanced Science.