A team of scientists, led by Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.
A team of UC San Diego biophysicists used quantitative models of bacterial growth to discover the bizarre way by which antibiotic resistance allows bacteria to multiply in the presence of antibiotics, a growing health problem in hospitals and nursing homes across the United States.
Expanding their efforts to keep citizens safe on San Diego roadways, UC San Diego’s Training, Research and Education for Driving Safety (TREDS) program announced today that they are launching a new distracted driving education project called Just Drive - Take Action Against Distraction, a one hour class free of charge offered to businesses in San Diego.
Nanosponges that soak up a dangerous pore-forming toxin produced by MRSA (methicillin-resistant Staphylococcus aureus) could serve as a safe and effective vaccine against this toxin. This “nanosponge vaccine” enabled the immune systems of mice to block the adverse effects of the alpha-haemolysin toxin from MRSA—both within the bloodstream and on the skin. Nanoengineers from the University of California, San Diego described the safety and efficacy of this nanosponge vaccine in the December 1 issue of Nature Nanotechnology.
A key pillar of “the scientific method” is reproducibility, one way to prove another scientist’s experimental claims. If the experiment and its results can be reproduced, the validity of the work is considerably strengthened.
Using advanced methodologies that pit drug compounds against specific types of malaria parasite cells, an international team of scientists, including researchers at the University of California, San Diego School of Medicine and the Genomics Institute of the Novartis Research Foundation, have identified a potential new weapon and approach for attacking the parasites that cause malaria.
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