Regulating Single Protein Prompts Fibroblasts to Become Neurons
Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells into functional neurons. The findings, which could have far-reaching implications for the development of new treatments for neurodegenerative diseases like Huntington’s, Parkinson’s and Alzheimer’s, will be published online in advance of the January 17 issue of the journal Cell.