An international team of scientists, led by researchers from the department of pediatrics at the UC San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.
Researchers from UC San Diego, the University of California Los Angeles and Indiana University report having found, for the first time, that atrial fibrillation or irregular heart rhythms is caused by small electrical sources within the heart, in the form of electrical spinning tops (“rotors”) or focal beats. Importantly, they found a way of detecting these key sources, then precisely targeting them for therapy that can shut them down in minutes with long lasting results.
This year, for the first time, external funding for sponsored research by scientists at Scripps Institution of Oceanography at UC San Diego exceeds $150 million (excluding ARRA* funding). Such funding arises from innovations and ideas of Scripps scientists and researchers who perform initial exploration of the concepts and compete in rigorous external competitive processes for funding.
Using a two-photon microscope capable of peering deep within living tissue, researchers at the University of California, San Diego School of Medicine have found new evidence that alpha-synuclein protein build-up inside neurons causes them to not only become “leaky,” but also to misfire due to calcium fluxes.
A new interdisciplinary collaboration at UC San Diego will study some of society's most perplexing and enduring problems. The Center for Investigations of Health and Educational Disparities will investigate the cultural, environmental, physical, behavioral, and biological causes of these disparities in the United States.
Dr. Karim Kader, associate clinical professor at the UC San Diego School of Medicine, together with a team of researchers from Wake Forest University School of Medicine, have developed a genetic test to predict a man’s risk for prostate cancer. Use of the test could reduce the need for repeat biopsies in men who have had a negative biopsy.
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