There are many unanswered questions about the mechanisms that contribute to the onset of type 1 diabetes. Researchers at University of California San Diego School of Medicine hope to answer some of them with two Type 1 Diabetes Special Statutory Funding Program grants from the National Institutes of Health totaling more than $5 million.
Viruses hijack the molecular machinery in human cells to survive and replicate, often damaging those host cells in the process. Researchers at the University of California San Diego School of Medicine discovered that, for cytomegalovirus (CMV), this process relies on a human protein called CPEB1. The study provides a potential new target for the development of CMV therapies.
Composer Roger Reynolds’ “FLiGHT,” which premieres Oct. 30-31 at the Park Avenue Armory in New York City, is the latest landmark in a career distinguished by a quest for new modes of making music. It combines spoken word, musical performance, computer sound processing and video to create an immersive multimedia experience.
Library event to feature renowned China scholar Paul Pickowicz, part of First China Trip.
Although only 10 percent of amyotrophic lateral sclerosis (ALS) cases are hereditary, a significant number of them are caused by mutations that affect proteins that bind RNA, a type of genetic material. University of California San Diego School of Medicine researchers studied several ALS cases with a mutation in a RNA-binding protein known as hnRNP A2/B1. In the study, they describe how damage to this protein contributes to ALS by scrambling crucial cellular messaging systems.
Researchers at University of California San Diego School of Medicine have discovered that Zika virus infection leads to modifications of both viral and human genetic material. These modifications — chemical tags known as methyl groups — influence viral replication and the human immune response.
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