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How a Yeast Cell Helps Crack Open the “Black Box” Behind Artificial Intelligence

Health & Behavior

UC San Diego School of Medicine researchers developed a visible neural network and used it to build DCell, a virtual model of a functioning brewer’s yeast cell. To do this, they amassed all knowledge of cell biology in one place and created a hierarchy of these cellular components. Then they mapped standard machine learning algorithms to this knowledgebase. DCell can be viewed at d-cell.ucsd.edu. The technical details are published March 5 in Nature Methods.

How a Yeast Cell Helps Crack Open the “Black Box” Behind Artificial Intelligence

A Campus Hub for Data Science

Science & Environment

A new institute at UC San Diego, which will be celebrated tomorrow at a campus dedication, is building on the university's strengths of multidisciplinary collaboration and data science to allow researchers across the campus to incorporate data science into their respective disciplines to better understand and make predictions about the world around us.

Beneficial Skin Bacteria Protect Against Skin Cancer

Health & Behavior

Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.

Beneficial Skin Bacteria Protect Against Skin Cancer

Jekyll and Hyde and Seek

Health & Behavior

Writing in the February 27 online issue of Science Signaling, researchers at University of California San Diego School of Medicine and Moores Cancer Center describe how a signaling protein that normally suppresses tumors can be manipulated (or re-programmed) by growth factors, turning it into a driver of malignant growth and metastasis.

New Online Tool Gives 3D View of Human Metabolic Processes

Health & Behavior

A new computational resource called Recon3D provides a 3D view of genes, proteins and metabolites involved in human metabolism. Researchers used the tool to map disease-related mutations on proteins and also probed how genes and proteins change in response to certain drugs. The work provides a better understanding of disease-causing mutations and could enable researchers to discover new uses for existing drug treatments.

New Online Tool Gives 3D View of Human Metabolic Processes

Researchers Use Human Neural Stem Cell Grafts to Repair Spinal Cord Injuries in Monkeys

Health & Behavior

Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries. The grafts not only survived, but grew hundreds of thousands of human axons and synapses, resulting in improved forelimb function in the monkeys.