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Gastrointestinal Hormone Measurably Improved Symptoms of Non-Alcoholic Fatty Liver Disease

Health & Behavior

Through a randomized, double-blind, placebo-controlled phase II clinical trial, researchers at University of California San Diego School of Medicine report that small doses of NGM282, a non-tumorigenic variant of an endocrine gastrointestinal hormone, can significantly and rapidly decrease liver fat content in patients with non-alcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). The findings, they say, represent an important proof-of-concept for the compound as there are currently no Food and Drug Administration-approved treatments for NAFLD and NASH.

Gastrointestinal Hormone Measurably Improved Symptoms of Non-Alcoholic Fatty Liver Disease

New Test Can Diagnose Heart Attack within an Hour

Health & Behavior

UC San Diego Health is the first hospital in California to use the fifth generation troponin test to diagnose heart attack. Approved in the United States in 2017, the more sensitive test can detect heart attack within an hour, as opposed to three to six hours.

New Test Can Diagnose Heart Attack within an Hour

SDSC Simulations Reveal How a Heart Drug Molecular Switch Is Turned On and Off

Health & Behavior

The study, published in the March 5 online edition of the Proceedings of the National Academy of Sciences (PNAS), describes how the supercomputing power of Gordon, Comet, and GPU clusters, all based at the San Diego Supercomputer Center at UC San Diego, were used with improved accelerated molecular dynamics (aMD) or Gaussian aMD (GaMD) to simulate the merger of a G-protein “mimetic nanobody” to a G-protein-coupled receptor (GPCR), the largest and most diverse group of membrane receptors in animals, plants, fungi, and protozoa.

SDSC Simulations Reveal How a Heart Drug Molecular Switch Is Turned On and Off

Koman Family Outpatient Pavilion Opens at UC San Diego Health on March 12

Health & Behavior

On March 12, 2018, UC San Diego Health will welcome its first patients to the Koman Family Outpatient Pavilion. Located on the La Jolla campus, the new 156,000-square-foot facility represents the most recent addition to the university’s world-class medical campus. In the past five years, UC San Diego Health has invested more than $1.3 billion dollars in patient care facilities for the community.

Koman Family Outpatient Pavilion Opens at UC San Diego Health on March 12

SDSC’s Health CI Division Now Meets NIST CUI Compliance Requirements

Health & Behavior

The Health Cyberinfrastructure Division of the San Diego Supercomputer Center (SDSC) at the University of California San Diego has expanded its cloud offerings to include a Controlled Unclassified Information (CUI)-compliant environment that is now available to researchers working with government contracts and grants.

SDSC’s Health CI Division Now Meets NIST CUI Compliance Requirements

Polygenic Risk Score May Identify Alzheimer’s Risk in Younger Populations

Health & Behavior

For the first time, an international team of scientists, led by researchers at University of California San Diego School of Medicine, have determined that an Alzheimer’s disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in their 50s. MCI is considered a precursor to AD.