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News Archive - School of Medicine

Greater Levels of Vitamin D Associated with Decreasing Risk of Breast Cancer

June 15, 2018

Researchers at University of California San Diego School of Medicine suggest higher levels of vitamin D are associated with decreasing risk of breast cancer. Their epidemiological study is published in the June 15 online issue of PLOS ONE, in collaboration with Creighton University, Medical University of South Carolina and GrassrootsHealth, an Encinitas-based nonprofit organization that promotes vitamin D research and its therapeutic benefits.

A Sprinkle of Platinum Nanoparticles Onto Graphene Makes Brain Probes More Sensitive

June 14, 2018

Graphene electrodes could enable higher quality imaging of brain cell activity thanks to new research by a team of engineers and neuroscientists at the University of California San Diego. The researchers developed a technique, using platinum nanoparticles, to lower the impedance of graphene electrodes by 100 times while keeping them transparent. In tests on transgenic mice, the electrodes were able to record and image neuronal activity (calcium ion spikes) at both the macroscale and single cell levels.

UC San Diego Launches New Center for Anti-Parasitic Drug Discovery and Development

June 13, 2018

Neglected tropical diseases are a group of chronic and disabling parasitic infections that primarily affect poor and underserved communities. These diseases affect more than 1 billion people globally, yet are rarely the target of new drug discovery efforts. Leveraging its strengths in molecular biology, clinical research and pharmaceutical sciences, the University of California San Diego has now launched a new Center for Anti-Parasitic Drug Discovery and Development to address this unmet need in global health.

Composition of Complex Sugars in Breast Milk May Prevent Future Food Allergies

June 12, 2018

The unique composition of a mother’s breastmilk may help to reduce food sensitization in her infant, report researchers at the University of California San Diego School of Medicine with colleagues in Canada.

What’s Inside Your Medical Record?

June 6, 2018

Patients at UC San Diego Health can now read the medical notes signed by their primary care physician. This move toward transparency is part of an international trend to make patients feel more in control of their health care.

Antibody Blocks Inflammation, Protects Mice from Hardened Arteries and Liver Disease

June 6, 2018

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged their lives.

Phase I Trial Finds Experimental Drug Safe in Treating Chronic Lymphocytic Leukemia

June 1, 2018

Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.

Stem Cell-Based Phase I Trial to Repair Spinal Cord Injuries Produces Encouraging Results

June 1, 2018

Researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.

Single Injection Alleviates Chemotherapy Pain for Months in Mice

May 29, 2018

UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.

Hot Cars Can Hit Life-Threatening Levels in Approximately One Hour

May 24, 2018

Researchers from University of California San Diego School of Medicine and Arizona State University found that if a car is parked in the sun on a summer day, the interior temperature can reach 116 degrees F. and the dashboard may exceed 165 degrees F. in approximately one hour — the time it can take for a young child trapped in a car to suffer fatal injuries.
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