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News Archive - School of Medicine

Using CRISPR to Reverse Retinitis Pigmentosa and Restore Visual Function

April 21, 2017

Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.

Rock Tour “Text2Give” Supports Immunotherapy at UC San Diego Health

April 19, 2017

Rock star drummer Rikki Rockett feels very lucky to be on tour with his band, Poison. A year ago, he didn’t know if he would survive tongue cancer but after participating in an immunotherapy clinical trial at Moores Cancer Center at UC San Diego Health, he was declared cancer-free in July 2016. To give back, Rockett is now asking concert-goers to join him in supporting immunotherapy at Moores Cancer Center.

Calling High School Students for UC San Diego’s Mentor Assistance Program

April 18, 2017

San Diego-area high school students interested in pursuing a career in scientifically-based research are invited to apply to UC San Diego’s Mentor Assistance Program (MAP), a campus-wide initiative designed to engage students in a mentoring relationship with an expert from a vast array of disciplines.

UC San Diego Health Scores an A for Safety and Quality from Leapfrog Group

April 17, 2017

The Leapfrog Group, a nonprofit organization that advocates quality, safety and transparency in the U.S. health care system, has named UC San Diego Health to its biannual list of hospitals with the highest safety standards in the country. UC San Diego Health hospitals in Hillcrest and La Jolla were among just 823 health care facilities nationwide to receive a grade of A for excellence in safety and quality.

UC San Diego Honors Entrepreneurs-in-Residence with Reception, Apr. 17

April 17, 2017

UC San Diego’s Office of Innovation and Commercialization (OIC) launched the Entrepreneurs-in-Residence (EIR) program in 2015 to accelerate the creation of new startup companies. The OIC, a Research Affairs unit, will honor the newly appointed 2017 EIR cohort and thank the 2016 cohort for their hard work with a reception, Apr. 17, at Bella Vista Social Club and Caffé in the Sanford Consortium.

Researchers Develop New Tools to Optimize CHO Cell Lines for Making Biologic Drugs

April 13, 2017

Chinese hamster ovary (CHO) cells are the workhorses behind more than half of the top-selling biologics on the market today. Humira, Avastin and Rituxan are a few. Researchers at the UC San Diego CHO Systems Biology Center are developing new tools, such as genome-scale metabolic models, to optimize CHO cell production of biologic drugs in the hope of driving down their costs.

CHO Systems Biology Center Pioneers Efforts to Improve Cell Production of High-Value Pharmaceuticals

April 13, 2017

Optimizing CHO (Chinese hamster ovary) cell lines to accelerate biologic drug development is a goal of the CHO Systems Biology Center at the University of California San Diego Jacobs School of Engineering. Center researchers are developing new technologies and training the next generation of cell line engineers and systems biology specialists to advance CHO cell engineering research.

In Four Related Papers, Researchers Describe New and Improved Tools for Stem Cell Research

April 6, 2017

In a new paper, a large team of researchers led by senior author Kelly Frazer, PhD, professor of pediatrics and director of the Institute for Genomic Medicine at University of California San Diego School of Medicine, describe a new collection of 222 systematically derived and characterized iPSC lines generated as part of the National Heart, Lung and Blood Institute’s NextGen consortium.

Birth Weight is Risk Factor for Fatty Liver Disease in Children

April 4, 2017

Researchers at University of California San Diego School of Medicine, with a cohort of clinical collaborators from across the United States, have demonstrated the impact of low and high birth weights in developing Non Alcoholic Fatty Liver Disease (NAFLD), a chronic disease that often leads to a need for organ transplantation.

Researchers Find New Genetic Links Underlying Progressively Blinding Eye Disease

March 30, 2017

Researchers at University of California San Diego School of Medicine, with colleagues at Case Western University, Duke University, the National Institutes of Health and elsewhere, have identified three novel genomic loci — distinct stretches of genetic material on chromosomes — linked to Fuchs endothelial corneal dystrophy (FECD), which often clusters in families and is roughly 39 percent heritable.
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