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News Archive - School of Medicine

Researchers Produce First Comprehensive Genomic Map of Head and Neck Cancers

January 29, 2015

A team that includes scores of researchers from across the country representing dozens of universities and medical institutions has produced the most comprehensive integrative analysis yet of head and neck squamous cell carcinomas (HNSCCs), a particularly malignant and deadly type of tumor that accounts for roughly 3 percent of all cancers in the United States.

UC San Diego, UC San Francisco Launch New Cancer Cell Mapping Initiative

January 29, 2015

Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project – dubbed the Cancer Cell Map Initiative or CCMI – to determine how all of the components of a cancer cell interact.

Friedmann Named 2015 Japan Prize Winner

January 28, 2015

Theodore Friedmann, MD, professor in the Department of Pediatrics at University of California, San Diego School of Medicine was named today one of three recipients of the 2015 Japan Prize, a prestigious international award honoring laureates whose “original and outstanding achievements in science and technology have advanced the frontiers of knowledge and served the cause of peace and prosperity for mankind.”

3D Enzyme Model Provides New Tool for Anti-Inflammatory Drug Development

January 26, 2015

To better understand PLA2 enzymes and help drive therapeutic drug development, researchers at University of California, San Diego School of Medicine developed 3D computer models that show exactly how two PLA2 enzymes extract their substrates from cellular membranes. The new tool is described in a paper published online the week of Jan. 26 by the Proceedings of the National Academy of Sciences.

Region’s First Camp for Stroke Survivors and Caregivers at UC San Diego

January 22, 2015

On Jan. 23-25, more than 15 stroke survivors and their caregivers will go on a mini-vacation in La Jolla, CA, as part of a therapeutic retreat for those whose lives have been affected – sometimes turned upside down – by stroke. The 50s-themed stroke camp is being co-hosted by UC San Diego Health System, which has one of the nation’s first certified Comprehensive Stroke Centers.

Pictured Together for the First Time: a Chemokine and its Receptor

January 22, 2015

Researchers at University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences and the Bridge Institute at the University of Southern California report the first crystal structure of the cellular receptor CXCR4 bound to an immune signaling protein called a chemokine. The structure answers longstanding questions about a molecular interaction that plays an important role in human development, immune responses, cancer metastasis and HIV infections.

Enzymes Believed to Promote Cancer Actually Suppress Tumors

January 22, 2015

Upending decades-old dogma, a team of scientists at the University of California, San Diego School of Medicine say enzymes long categorized as promoting cancer are, in fact, tumor suppressors and that current clinical efforts to develop inhibitor-based drugs should instead focus on restoring the enzymes’ activities.

New Cellular Pathway Triggering Allergic Asthma Response Identified

January 19, 2015

Researchers at the University of California, San Diego School of Medicine, with collaborators in Korea and Scotland, have identified a novel signaling pathway critical to the immune response of cells associated with the initiation of allergic asthma. The discovery, they say, could point the way to new therapies that suppress the inflammatory allergic response, offering potential relief to millions of Americans with the chronic lung condition and potentially other allergic diseases.

Century-Old Drug Reverses Autism-like Symptoms in Fragile X Mouse Model

January 15, 2015

Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study published in this week’s online issue of Molecular Autism, suggests that a genetic form of autism-like symptoms in mice are also corrected with the drug, even when treatment was started in young adult mice.

UC San Diego School of Medicine Named One of Nation’s Top Residency Programs

January 13, 2015

UC San Diego School of Medicine was today named one of the nation’s top residency training programs in 10 specialties by Doximity. The Doximity report included more than 50,000 peer nominations from board-certified US physicians, and evaluated 3,691 residency training programs across 20 specialties.
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