June 12, 2018
June 12, 2018 —
The unique composition of a mother’s breastmilk may help to reduce food sensitization in her infant, report researchers at the University of California San Diego School of Medicine with colleagues in Canada.
June 6, 2018
June 6, 2018 —
Patients at UC San Diego Health can now read the medical notes signed by their primary care physician. This move toward transparency is part of an international trend to make patients feel more in control of their health care.
June 6, 2018
June 6, 2018 —
Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the arteries and liver disease, and prolonged their lives.
June 1, 2018
June 1, 2018 —
Reporting results from a first-in-human phase I clinical trial, researchers at University of California San Diego School of Medicine have found that treatment with cirmtuzumab, an experimental monoclonal antibody-based drug, measurably inhibited the “stemness” of chronic lymphocytic leukemia cancer (CLL) cells — their ability to self-renew and resist terminal differentiation and senescence.
June 1, 2018
June 1, 2018 —
Researchers at University of California San Diego School of Medicine report that a first-in-human phase I clinical trial in which neural stem cells were transplanted into participants with chronic spinal cord injuries produced measurable improvement in three of four subjects, with no serious adverse effects.
May 29, 2018
May 29, 2018 —
UC San Diego School of Medicine researchers found that treating mice with a single spinal injection of a protein called AIBP — and thus switching “off” TLR4, a pro-inflammatory molecule — prevented and reversed inflammation and cellular events associated with pain processing. As reported May 29 by Cell Reports, the treatment alleviated chemotherapy pain in mice for two months with no side effects.
May 24, 2018
May 24, 2018 —
Researchers from University of California San Diego School of Medicine and Arizona State University found that if a car is parked in the sun on a summer day, the interior temperature can reach 116 degrees F. and the dashboard may exceed 165 degrees F. in approximately one hour — the time it can take for a young child trapped in a car to suffer fatal injuries.
May 23, 2018
May 23, 2018 —
In a new paper, published in the May 23 online issue of Science Translational Medicine, researchers at University of California San Diego School of Medicine report that adult rat myelin actually stimulated axonal outgrowth in rat neural precursor cells (NPCs) and human induced pluripotent (iPSC)-derived neural stem cells (NSCs).
May 18, 2018
May 18, 2018 —
Researchers at University of California San Diego School of Medicine and their collaborators have developed a technique that allows them to speed up or slow down human heart cells growing in a dish on command — simply by shining a light on them and varying its intensity. The cells are grown on a material called graphene, which converts light into electricity, providing a more realistic environment than standard plastic or glass laboratory dishes.
May 16, 2018
May 16, 2018 —
A UC San Diego-led team has identified a gene that helps prevent the harmful buildup of proteins that can lead to neurological disorders such as Alzheimer’s and Parkinson’s disease. As published in Nature, the researchers found that the “Ankrd16” gene acts like a failsafe in proofreading and correcting errors to avoid the abnormal production of improper proteins.
